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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
31.52
Human Site:
S319
Identified Species:
63.03
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S319
L
T
R
L
L
K
D
S
L
G
G
N
C
Q
T
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S319
L
T
R
L
L
K
D
S
L
G
G
N
C
Q
T
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S319
L
T
R
L
L
K
D
S
L
G
G
N
C
Q
T
Dog
Lupus familis
XP_542544
899
102337
S319
L
T
R
L
L
K
D
S
L
G
G
N
C
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
S319
L
T
R
L
L
K
D
S
L
G
G
N
C
Q
T
Rat
Rattus norvegicus
Q4KLL9
826
91176
S317
L
T
R
L
L
K
D
S
I
G
G
N
C
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
E200
L
H
E
P
K
T
A
E
E
I
L
Q
M
L
D
Chicken
Gallus gallus
Q5ZLK6
797
86563
V288
S
L
L
A
L
I
N
V
I
N
A
L
A
D
A
Frog
Xenopus laevis
Q7ZXX2
997
114958
S310
L
T
R
L
L
K
D
S
L
G
G
N
S
R
T
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
S317
L
T
R
L
L
K
D
S
L
G
G
N
C
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
V208
L
E
V
Y
N
E
N
V
Q
D
L
L
H
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
D190
A
F
V
V
N
N
A
D
D
M
D
R
I
M
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
6.6
6.6
86.6
93.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
20
93.3
100
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
17
0
0
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
59
0
0
% C
% Asp:
0
0
0
0
0
0
67
9
9
9
9
0
0
9
9
% D
% Glu:
0
9
9
0
0
9
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
67
67
0
0
0
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
17
9
0
0
9
0
0
% I
% Lys:
0
0
0
0
9
67
0
0
0
0
0
0
0
9
0
% K
% Leu:
84
9
9
67
75
0
0
0
59
0
17
17
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% M
% Asn:
0
0
0
0
17
9
17
0
0
9
0
67
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
9
0
42
0
% Q
% Arg:
0
0
67
0
0
0
0
0
0
0
0
9
0
25
0
% R
% Ser:
9
0
0
0
0
0
0
67
0
0
0
0
9
0
9
% S
% Thr:
0
67
0
0
0
9
0
0
0
0
0
0
0
0
75
% T
% Val:
0
0
17
9
0
0
0
17
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _