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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPTC7 All Species: 21.52
Human Site: S148 Identified Species: 36.41
UniProt: Q8NI37 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NI37 NP_644812.1 304 32646 S148 I V V L D R T S H R L H T A N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107506 304 32637 S148 I V V L D R T S H R L H T A N
Dog Lupus familis XP_543391 421 44709 S265 I V V L D R T S H R L H T A N
Cat Felis silvestris
Mouse Mus musculus Q6NVE9 310 33030 S154 I V V L D R S S H R L H T A N
Rat Rattus norvegicus NP_001100611 307 32828 S151 I V V L D R S S H R L H T A N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505942 231 25205 L83 H R L H T A N L G D S G F L V
Chicken Gallus gallus XP_415161 297 32265 N148 S H R L H T A N L G D S G F L
Frog Xenopus laevis Q6GR25 297 32409 N148 S H R L H T A N L G D S G F L
Zebra Danio Brachydanio rerio Q5U3N5 297 32325 N148 S H R L H T A N L G D S G F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VAH4 314 34820 D157 L A T M H R K D C T L Y T A N
Honey Bee Apis mellifera XP_624085 303 32941 T149 V I V L N K E T S S I Y A A N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792667 1013 112492 N855 I V I F D S D N K T V A S A N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SUK9 467 50278 A308 K S Q G S S T A C I I A L T N
Baker's Yeast Sacchar. cerevisiae P38797 343 37764 N183 I V A H F P S N G K L E V A N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 72.2 N.A. 97 98 N.A. 75.3 94.4 90.4 91.4 N.A. 40.1 55.2 N.A. 20.5
Protein Similarity: 100 N.A. 99.6 72.2 N.A. 98 99 N.A. 75.9 95.3 93.4 94 N.A. 56.3 73.3 N.A. 24.7
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 0 6.6 6.6 6.6 N.A. 33.3 26.6 N.A. 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 13.3 13.3 13.3 N.A. 53.3 73.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. 20.5 32.3 N.A.
Protein Similarity: N.A. N.A. N.A. 32.5 46 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 22 8 0 0 0 15 8 65 0 % A
% Cys: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 43 0 8 8 0 8 22 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 0 8 8 0 0 0 0 0 0 0 8 22 0 % F
% Gly: 0 0 0 8 0 0 0 0 15 22 0 8 22 0 0 % G
% His: 8 22 0 15 29 0 0 0 36 0 0 36 0 0 0 % H
% Ile: 50 8 8 0 0 0 0 0 0 8 15 0 0 0 0 % I
% Lys: 8 0 0 0 0 8 8 0 8 8 0 0 0 0 0 % K
% Leu: 8 0 8 65 0 0 0 8 22 0 50 0 8 8 22 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 8 36 0 0 0 0 0 0 72 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 22 0 0 43 0 0 0 36 0 0 0 0 0 % R
% Ser: 22 8 0 0 8 15 22 36 8 8 8 22 8 0 0 % S
% Thr: 0 0 8 0 8 22 29 8 0 15 0 0 43 8 0 % T
% Val: 8 50 43 0 0 0 0 0 0 0 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _