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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM58
All Species:
11.82
Human Site:
S218
Identified Species:
43.33
UniProt:
Q8NG06
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NG06
NP_056246.3
486
54766
S218
T
L
Q
R
L
R
E
S
K
S
R
L
V
Q
Q
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
N229
I
L
Q
R
L
R
E
N
A
A
H
L
G
D
K
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
S219
I
L
K
S
L
T
K
S
E
T
E
M
V
Q
Q
Dog
Lupus familis
XP_539335
517
58600
N249
T
L
Q
R
L
R
E
N
K
N
R
L
V
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q5NCC9
485
55352
S217
T
L
Q
R
L
R
D
S
R
N
R
L
A
Q
Q
Rat
Rattus norvegicus
Q6MFZ5
488
56376
N229
I
L
Q
R
L
R
E
N
A
A
H
L
G
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516756
1149
124804
S354
T
L
R
R
L
R
E
S
R
A
R
L
A
Q
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39
31.3
76.7
N.A.
79
39.1
N.A.
22.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
55
49.2
83.5
N.A.
88
57.7
N.A.
30.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
46.6
40
86.6
N.A.
73.3
46.6
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
66.6
73.3
100
N.A.
93.3
66.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
29
43
0
0
29
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
15
0
0
0
0
0
0
29
0
% D
% Glu:
0
0
0
0
0
0
72
0
15
0
15
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% H
% Ile:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
0
0
0
15
0
29
0
0
0
0
0
15
% K
% Leu:
0
100
0
0
100
0
0
0
0
0
0
86
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
43
0
29
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
72
0
0
0
0
0
0
0
0
0
0
72
58
% Q
% Arg:
0
0
15
86
0
86
0
0
29
0
58
0
0
0
29
% R
% Ser:
0
0
0
15
0
0
0
58
0
15
0
0
0
0
0
% S
% Thr:
58
0
0
0
0
15
0
0
0
15
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _