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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DMBX1
All Species:
23.03
Human Site:
S220
Identified Species:
46.06
UniProt:
Q8NFW5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFW5
NP_671725.1
382
41198
S220
E
K
S
P
G
A
D
S
K
G
L
G
C
K
R
Chimpanzee
Pan troglodytes
XP_524575
402
43501
S240
E
K
S
P
G
A
D
S
K
G
L
G
C
K
R
Rhesus Macaque
Macaca mulatta
XP_001098052
414
44695
S252
E
K
S
P
G
A
E
S
K
G
L
G
C
K
R
Dog
Lupus familis
XP_853026
566
60421
S408
E
K
S
P
G
A
E
S
K
G
L
G
C
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZK4
381
41097
S218
E
K
S
P
G
S
E
S
K
V
P
G
C
K
R
Rat
Rattus norvegicus
NP_001101431
376
40677
S213
E
K
S
P
G
S
E
S
K
V
L
G
C
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510717
362
39755
F203
Q
A
D
R
E
E
E
F
Q
E
G
A
E
E
S
Chicken
Gallus gallus
XP_422451
367
40982
L209
E
E
E
F
K
S
T
L
D
E
A
K
V
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8JI10
388
42697
Q222
D
K
E
E
E
I
K
Q
H
R
E
D
L
K
V
Tiger Blowfish
Takifugu rubipres
NP_001027814
380
41393
S208
T
S
P
E
P
S
D
S
E
S
A
A
E
D
N
Fruit Fly
Dros. melanogaster
NP_001097075
607
63374
M284
P
I
E
V
G
G
P
M
S
L
T
T
G
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781076
438
48838
E271
D
V
G
K
F
R
E
E
E
D
R
M
A
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
89.1
56.5
N.A.
93.9
91.3
N.A.
76.6
76.9
N.A.
71.6
65.7
22.7
N.A.
N.A.
32.6
Protein Similarity:
100
93.7
89.8
61.1
N.A.
95.2
92.9
N.A.
81.9
83.7
N.A.
77.8
72.7
32.7
N.A.
N.A.
48.8
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
0
6.6
N.A.
13.3
13.3
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
26.6
26.6
N.A.
20
26.6
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
34
0
0
0
0
17
17
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% C
% Asp:
17
0
9
0
0
0
25
0
9
9
0
9
0
17
0
% D
% Glu:
59
9
25
17
17
9
50
9
17
17
9
0
17
9
0
% E
% Phe:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
59
9
0
0
0
34
9
50
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
59
0
9
9
0
9
0
50
0
0
9
0
59
9
% K
% Leu:
0
0
0
0
0
0
0
9
0
9
42
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
9
0
9
50
9
0
9
0
0
0
9
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
9
0
0
0
9
9
0
0
9
59
% R
% Ser:
0
9
50
0
0
34
0
59
9
9
0
0
0
9
9
% S
% Thr:
9
0
0
0
0
0
9
0
0
0
9
9
0
0
0
% T
% Val:
0
9
0
9
0
0
0
0
0
17
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _