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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IPMK
All Species:
15.76
Human Site:
S279
Identified Species:
28.89
UniProt:
Q8NFU5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NFU5
NP_689416.1
416
47222
S279
T
L
A
E
K
F
L
S
K
G
Q
L
S
D
T
Chimpanzee
Pan troglodytes
XP_507801
416
47184
S279
T
L
A
E
K
F
L
S
K
G
Q
L
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001091935
430
48294
S293
T
L
A
E
K
F
L
S
K
G
Q
L
S
D
T
Dog
Lupus familis
XP_546106
416
46981
S279
T
L
V
E
K
F
L
S
K
G
Q
L
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT16
396
44434
P265
G
R
F
L
S
K
G
P
L
T
D
A
D
G
L
Rat
Rattus norvegicus
Q99NI4
396
44391
A265
G
R
F
L
S
K
G
A
L
S
D
A
D
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507718
408
46501
P270
F
S
E
K
R
F
V
P
K
G
Q
L
S
E
E
Chicken
Gallus gallus
XP_001233281
439
48329
P299
L
A
E
K
R
G
V
P
K
G
L
L
S
G
G
Frog
Xenopus laevis
NP_001087711
402
45023
V265
T
L
V
E
K
R
A
V
P
K
G
Q
F
T
D
Zebra Danio
Brachydanio rerio
NP_001073533
372
41821
S242
S
R
F
N
F
Y
A
S
S
L
L
F
V
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608535
309
35312
K179
R
H
G
K
D
Y
G
K
S
L
N
V
E
G
F
Honey Bee
Apis mellifera
XP_001120810
403
45768
T273
T
N
D
T
R
L
L
T
R
S
R
T
S
L
P
Nematode Worm
Caenorhab. elegans
NP_502402
312
35799
V182
I
H
R
S
D
N
Q
V
E
V
R
D
K
D
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
86.9
90.8
N.A.
81
82.9
N.A.
75.4
73.1
64.1
51.9
N.A.
28.1
20.6
20.6
N.A.
Protein Similarity:
100
100
89.5
96.3
N.A.
87.5
88.6
N.A.
82.4
81.3
77.1
64.4
N.A.
43.2
41.3
36.7
N.A.
P-Site Identity:
100
100
100
80
N.A.
0
0
N.A.
40
26.6
26.6
6.6
N.A.
0
20
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
0
6.6
N.A.
66.6
46.6
26.6
20
N.A.
20
46.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
24
0
0
0
16
8
0
0
0
16
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
16
0
0
0
0
0
16
8
16
31
8
% D
% Glu:
0
0
16
39
0
0
0
0
8
0
0
0
8
8
16
% E
% Phe:
8
0
24
0
8
39
0
0
0
0
0
8
8
0
8
% F
% Gly:
16
0
8
0
0
8
24
0
0
47
8
0
0
31
8
% G
% His:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
24
39
16
0
8
47
8
0
0
8
0
0
% K
% Leu:
8
39
0
16
0
8
39
0
16
16
16
47
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
24
8
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
39
8
0
0
0
% Q
% Arg:
8
24
8
0
24
8
0
0
8
0
16
0
0
0
0
% R
% Ser:
8
8
0
8
16
0
0
39
16
16
0
0
54
0
0
% S
% Thr:
47
0
0
8
0
0
0
8
0
8
0
8
0
8
24
% T
% Val:
0
0
16
0
0
0
16
16
0
8
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
16
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _