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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC50
All Species:
4.24
Human Site:
T536
Identified Species:
10.37
UniProt:
Q8NEP3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEP3
NP_848547.4
725
80026
T536
T
R
T
E
D
L
E
T
I
R
L
E
T
K
E
Chimpanzee
Pan troglodytes
XP_511137
725
80181
T536
M
R
T
E
D
L
E
T
I
R
L
E
T
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536764
762
84049
D577
S
P
E
T
V
A
G
D
E
D
L
E
V
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2H9
634
69685
F449
V
E
I
K
E
R
L
F
I
D
D
L
P
D
L
Rat
Rattus norvegicus
Q6AYH9
633
69937
L448
A
L
E
T
K
E
K
L
F
I
D
D
L
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516863
630
71015
V445
V
H
E
E
V
V
E
V
K
G
S
G
I
Q
Y
Chicken
Gallus gallus
XP_414069
621
70519
I436
E
Y
A
E
I
K
Q
I
K
H
E
T
P
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZV84
555
62127
Q370
S
A
S
D
D
S
D
Q
S
Q
P
Q
P
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393975
1711
194833
R1111
L
F
N
E
M
N
Y
R
S
G
V
E
K
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782591
513
58706
L328
P
K
E
K
A
C
T
L
A
W
W
E
G
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
N.A.
58.5
N.A.
56.9
57.3
N.A.
39.4
40.6
N.A.
35
N.A.
N.A.
21.3
N.A.
31.4
Protein Similarity:
100
98.4
N.A.
66.9
N.A.
65.6
67
N.A.
55
54.2
N.A.
49.5
N.A.
N.A.
29.9
N.A.
46.4
P-Site Identity:
100
93.3
N.A.
26.6
N.A.
6.6
0
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
33.3
N.A.
20
20
N.A.
26.6
26.6
N.A.
53.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
10
10
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
30
0
10
10
0
20
20
10
0
10
10
% D
% Glu:
10
10
40
50
10
10
30
0
10
0
10
50
0
10
40
% E
% Phe:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
20
0
10
10
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
0
10
30
10
0
0
10
0
0
% I
% Lys:
0
10
0
20
10
10
10
0
20
0
0
0
10
30
10
% K
% Leu:
10
10
0
0
0
20
10
20
0
0
30
10
10
0
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
20
0
% N
% Pro:
10
10
0
0
0
0
0
0
0
0
10
0
30
10
0
% P
% Gln:
0
0
0
0
0
0
10
10
0
10
0
10
0
10
0
% Q
% Arg:
0
20
0
0
0
10
0
10
0
20
0
0
0
0
20
% R
% Ser:
20
0
10
0
0
10
0
0
20
0
10
0
0
0
0
% S
% Thr:
10
0
20
20
0
0
10
20
0
0
0
10
20
0
0
% T
% Val:
20
0
0
0
20
10
0
10
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _