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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHCBP1
All Species:
21.52
Human Site:
T422
Identified Species:
47.33
UniProt:
Q8NEM2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEM2
NP_079021.3
672
75660
T422
E
K
R
G
K
G
D
T
F
V
D
C
T
G
A
Chimpanzee
Pan troglodytes
XP_001160750
672
75675
T422
E
K
R
G
K
G
D
T
F
V
D
C
T
G
A
Rhesus Macaque
Macaca mulatta
XP_001113495
672
75581
T422
E
K
R
G
K
G
D
T
F
V
D
C
T
G
A
Dog
Lupus familis
XP_532571
666
75430
T416
E
K
R
G
K
G
D
T
F
V
D
C
T
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z179
668
75899
T422
E
K
R
G
K
G
D
T
F
V
D
C
T
G
M
Rat
Rattus norvegicus
XP_001077162
628
71395
Q400
I
S
G
V
K
F
I
Q
H
D
S
V
E
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505510
494
55400
E267
F
V
Q
H
E
S
V
E
G
I
L
S
V
H
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPE9
699
79103
T428
E
K
M
G
K
G
D
T
F
V
A
C
S
G
A
Zebra Danio
Brachydanio rerio
NP_956137
732
82215
A476
E
K
R
N
K
G
D
A
F
V
E
S
T
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119910
496
56207
G269
K
L
F
F
R
I
S
G
S
L
L
E
T
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780902
784
86552
I489
R
C
E
E
L
A
D
I
F
L
D
C
D
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
88.2
N.A.
77.8
74.1
N.A.
60.5
N.A.
58.6
50.1
N.A.
N.A.
21.1
N.A.
23.2
Protein Similarity:
100
99.5
98.5
93.5
N.A.
86.9
81.8
N.A.
65.9
N.A.
74.9
66.9
N.A.
N.A.
37.3
N.A.
43.4
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
0
N.A.
80
73.3
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
20
N.A.
86.6
80
N.A.
N.A.
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
46
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
64
0
0
0
% C
% Asp:
0
0
0
0
0
0
73
0
0
10
55
0
10
0
0
% D
% Glu:
64
0
10
10
10
0
0
10
0
0
10
10
10
0
0
% E
% Phe:
10
0
10
10
0
10
0
0
73
0
0
0
0
0
0
% F
% Gly:
0
0
10
55
0
64
0
10
10
0
0
0
0
73
0
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
10
10
% H
% Ile:
10
0
0
0
0
10
10
10
0
10
0
0
0
0
10
% I
% Lys:
10
64
0
0
73
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
19
19
0
0
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
55
0
10
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
10
0
0
0
10
10
0
10
0
10
19
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
55
0
0
0
0
64
0
0
% T
% Val:
0
10
0
10
0
0
10
0
0
64
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _