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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHCBP1
All Species:
17.58
Human Site:
S252
Identified Species:
38.67
UniProt:
Q8NEM2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NEM2
NP_079021.3
672
75660
S252
V
D
Y
H
N
L
L
S
Q
C
E
E
S
Y
R
Chimpanzee
Pan troglodytes
XP_001160750
672
75675
S252
V
D
Y
R
N
L
L
S
Q
C
E
E
S
Y
R
Rhesus Macaque
Macaca mulatta
XP_001113495
672
75581
S252
V
D
Y
R
N
L
L
S
Q
C
E
E
S
Y
R
Dog
Lupus familis
XP_532571
666
75430
S246
V
D
Y
H
N
L
L
S
Q
C
E
E
S
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z179
668
75899
S252
V
D
Y
H
N
L
L
S
Q
C
E
E
S
Y
R
Rat
Rattus norvegicus
XP_001077162
628
71395
E238
C
N
S
D
S
E
Q
E
N
I
S
M
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505510
494
55400
V105
E
L
E
N
V
S
M
V
E
G
L
R
L
Y
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GPE9
699
79103
L253
A
E
Y
S
S
L
L
L
Q
C
E
E
V
Y
M
Zebra Danio
Brachydanio rerio
NP_956137
732
82215
L303
V
A
E
Y
H
S
L
L
A
L
C
S
E
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119910
496
56207
I107
D
K
Y
D
V
P
L
I
D
L
Y
P
T
H
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780902
784
86552
L315
V
R
K
H
Q
K
A
L
S
E
C
L
D
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
88.2
N.A.
77.8
74.1
N.A.
60.5
N.A.
58.6
50.1
N.A.
N.A.
21.1
N.A.
23.2
Protein Similarity:
100
99.5
98.5
93.5
N.A.
86.9
81.8
N.A.
65.9
N.A.
74.9
66.9
N.A.
N.A.
37.3
N.A.
43.4
P-Site Identity:
100
93.3
93.3
100
N.A.
100
0
N.A.
6.6
N.A.
53.3
13.3
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
13.3
N.A.
26.6
N.A.
66.6
26.6
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
55
19
0
0
0
0
% C
% Asp:
10
46
0
19
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
10
10
19
0
0
10
0
10
10
10
55
55
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
37
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
0
0
10
0
0
0
0
0
0
0
19
0
% K
% Leu:
0
10
0
0
0
55
73
28
0
19
10
10
10
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% M
% Asn:
0
10
0
10
46
0
0
0
10
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
55
0
0
0
0
0
0
% Q
% Arg:
0
10
0
19
0
0
0
0
0
0
0
10
0
0
46
% R
% Ser:
0
0
10
10
19
19
0
46
10
0
10
10
46
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
64
0
0
0
19
0
0
10
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
64
10
0
0
0
0
0
0
10
0
0
64
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _