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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC109A
All Species:
16.67
Human Site:
Y158
Identified Species:
45.83
UniProt:
Q8NE86
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NE86
NP_612366.1
351
39867
Y158
L
V
I
N
D
L
T
Y
H
V
R
P
P
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001104618
310
36104
I151
Q
L
Y
T
T
L
C
I
E
Q
H
Q
L
N
K
Dog
Lupus familis
XP_546160
317
36983
I158
Q
L
Y
T
T
L
C
I
E
Q
H
Q
L
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UMR5
350
39663
Y157
L
V
I
N
D
L
T
Y
H
V
R
P
P
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506201
437
50581
Y244
L
V
I
N
D
R
T
Y
D
V
R
P
P
V
K
Chicken
Gallus gallus
XP_426497
344
39560
Y151
L
I
I
N
D
I
T
Y
H
V
R
P
P
K
R
Frog
Xenopus laevis
NP_001087837
319
37200
Q160
R
L
Y
T
A
L
H
Q
E
E
H
H
L
K
K
Zebra Danio
Brachydanio rerio
Q08BI9
376
42846
Y182
L
V
I
N
D
T
S
Y
L
V
Q
P
P
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787049
316
36823
K153
K
L
I
S
E
D
A
K
T
L
D
D
V
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86.3
85.7
N.A.
96
N.A.
N.A.
40.5
85.7
49.2
65.1
N.A.
N.A.
N.A.
N.A.
46.4
Protein Similarity:
100
N.A.
87.1
87.1
N.A.
97.7
N.A.
N.A.
57.2
91.4
67.8
76.3
N.A.
N.A.
N.A.
N.A.
65.5
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
100
N.A.
N.A.
73.3
86.6
13.3
66.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
20
20
N.A.
100
N.A.
N.A.
80
100
26.6
86.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
56
12
0
0
12
0
12
12
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
34
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
34
0
34
12
0
0
0
% H
% Ile:
0
12
67
0
0
12
0
23
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
12
0
0
0
0
0
56
45
% K
% Leu:
56
45
0
0
0
56
0
0
12
12
0
0
34
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
56
0
0
0
0
0
0
0
0
0
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
56
56
0
0
% P
% Gln:
23
0
0
0
0
0
0
12
0
23
12
23
0
0
0
% Q
% Arg:
12
0
0
0
0
12
0
0
0
0
45
0
0
12
45
% R
% Ser:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
12
% S
% Thr:
0
0
0
34
23
12
45
0
12
0
0
0
0
0
0
% T
% Val:
0
45
0
0
0
0
0
0
0
56
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _