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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC109A All Species: 2.42
Human Site: S14 Identified Species: 6.67
UniProt: Q8NE86 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NE86 NP_612366.1 351 39867 S14 R S L L L L L S S R G G G G G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104618 310 36104 S15 L Q V H Q R I S S W Q N L G V
Dog Lupus familis XP_546160 317 36983 V17 E T I V N T V V H Q R L S F W
Cat Felis silvestris
Mouse Mus musculus Q3UMR5 350 39663 C14 R S L L L L L C S R G G G G G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506201 437 50581 S100 V G D E F Q M S R P A G S S L
Chicken Gallus gallus XP_426497 344 39560 C14 R S L P L L L C R R R G A A A
Frog Xenopus laevis NP_001087837 319 37200 A14 L W R R I P V A A S C Q I R C
Zebra Danio Brachydanio rerio Q08BI9 376 42846 K38 S Q R H Q G T K T E A L S M S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787049 316 36823 H14 I R V Q L C Q H Q R G I L L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 86.3 85.7 N.A. 96 N.A. N.A. 40.5 85.7 49.2 65.1 N.A. N.A. N.A. N.A. 46.4
Protein Similarity: 100 N.A. 87.1 87.1 N.A. 97.7 N.A. N.A. 57.2 91.4 67.8 76.3 N.A. N.A. N.A. N.A. 65.5
P-Site Identity: 100 N.A. 20 0 N.A. 93.3 N.A. N.A. 13.3 53.3 0 0 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 N.A. 33.3 33.3 N.A. 93.3 N.A. N.A. 20 53.3 26.6 6.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 12 0 23 0 12 12 12 % A
% Cys: 0 0 0 0 0 12 0 23 0 0 12 0 0 0 12 % C
% Asp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 12 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 12 0 0 0 0 0 0 0 0 12 0 % F
% Gly: 0 12 0 0 0 12 0 0 0 0 34 45 23 34 23 % G
% His: 0 0 0 23 0 0 0 12 12 0 0 0 0 0 0 % H
% Ile: 12 0 12 0 12 0 12 0 0 0 0 12 12 0 0 % I
% Lys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % K
% Leu: 23 0 34 23 45 34 34 0 0 0 0 23 23 12 12 % L
% Met: 0 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 12 0 0 0 % N
% Pro: 0 0 0 12 0 12 0 0 0 12 0 0 0 0 0 % P
% Gln: 0 23 0 12 23 12 12 0 12 12 12 12 0 0 0 % Q
% Arg: 34 12 23 12 0 12 0 0 23 45 23 0 0 12 12 % R
% Ser: 12 34 0 0 0 0 0 34 34 12 0 0 34 12 12 % S
% Thr: 0 12 0 0 0 12 12 0 12 0 0 0 0 0 0 % T
% Val: 12 0 23 12 0 0 23 12 0 0 0 0 0 0 12 % V
% Trp: 0 12 0 0 0 0 0 0 0 12 0 0 0 0 12 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _