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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21A
All Species:
17.88
Human Site:
Y899
Identified Species:
39.33
UniProt:
Q8NDW8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDW8
NP_001098983.1
1320
150944
Y899
C
I
Q
F
A
E
H
Y
L
A
E
K
E
Y
D
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
Y899
C
I
Q
F
A
E
H
Y
L
A
E
K
E
Y
D
Rhesus Macaque
Macaca mulatta
XP_001083557
1313
149854
Y892
C
I
Q
F
A
E
H
Y
L
A
E
K
E
Y
D
Dog
Lupus familis
XP_542714
1222
139067
K850
A
K
V
Y
K
S
H
K
K
E
D
V
M
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0S4
1314
148598
H893
C
I
Q
I
G
E
H
H
L
A
E
K
D
Y
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
S894
C
A
E
L
A
K
H
S
A
A
Q
R
D
F
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC1
1312
148653
Y891
C
V
Q
L
A
E
H
Y
V
D
Q
R
N
Y
E
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
C899
C
A
E
I
A
K
H
C
S
S
Q
R
G
Y
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
Y845
L
L
S
L
A
K
L
Y
M
Q
T
N
N
L
D
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
L904
C
N
L
Q
A
E
L
L
Y
R
R
R
E
F
S
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
C895
C
S
Q
M
A
E
Q
C
S
T
Q
R
A
F
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.7
76.2
N.A.
76.6
N.A.
N.A.
49.2
N.A.
59.7
51.6
N.A.
N.A.
28.8
29
47.4
Protein Similarity:
100
99.8
98.3
83.1
N.A.
86.5
N.A.
N.A.
68.9
N.A.
75
72.2
N.A.
N.A.
47.7
49.7
68.7
P-Site Identity:
100
100
100
6.6
N.A.
73.3
N.A.
N.A.
26.6
N.A.
46.6
26.6
N.A.
N.A.
20
26.6
33.3
P-Site Similarity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
73.3
N.A.
80
66.6
N.A.
N.A.
40
40
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
0
82
0
0
0
10
46
0
0
10
0
0
% A
% Cys:
82
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
10
0
19
0
55
% D
% Glu:
0
0
19
0
0
64
0
0
0
10
37
0
37
10
28
% E
% Phe:
0
0
0
28
0
0
0
0
0
0
0
0
0
28
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
73
10
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
28
0
10
10
0
0
37
0
0
0
% K
% Leu:
10
10
10
28
0
0
19
10
37
0
0
0
0
10
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
10
19
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
55
10
0
0
10
0
0
10
37
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
10
46
0
0
0
% R
% Ser:
0
10
10
0
0
10
0
10
19
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% T
% Val:
0
10
10
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
46
10
0
0
0
0
55
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _