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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21A
All Species:
26.36
Human Site:
Y714
Identified Species:
58
UniProt:
Q8NDW8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDW8
NP_001098983.1
1320
150944
Y714
T
L
R
D
R
R
L
Y
I
R
C
Y
R
E
L
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
Y714
T
L
R
D
R
R
L
Y
I
R
C
Y
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001083557
1313
149854
Y707
T
L
R
D
R
R
L
Y
I
R
C
Y
R
E
L
Dog
Lupus familis
XP_542714
1222
139067
K698
W
Y
T
E
A
K
E
K
M
A
N
I
Y
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0S4
1314
148598
Y707
T
R
K
D
V
R
L
Y
I
G
C
Y
V
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
Y708
H
R
K
E
K
K
L
Y
A
S
C
Y
R
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC1
1312
148653
Y706
N
R
K
D
K
K
L
Y
I
G
C
Y
R
E
L
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
Y713
H
R
K
E
K
R
L
Y
V
S
C
Y
R
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
A693
K
T
H
Q
Y
T
K
A
I
N
Y
Y
R
D
V
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
F723
E
K
K
D
K
R
M
F
A
A
C
Y
R
E
L
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
Y709
H
R
K
D
K
K
L
Y
A
S
C
Y
R
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.7
76.2
N.A.
76.6
N.A.
N.A.
49.2
N.A.
59.7
51.6
N.A.
N.A.
28.8
29
47.4
Protein Similarity:
100
99.8
98.3
83.1
N.A.
86.5
N.A.
N.A.
68.9
N.A.
75
72.2
N.A.
N.A.
47.7
49.7
68.7
P-Site Identity:
100
100
100
0
N.A.
66.6
N.A.
N.A.
40
N.A.
60
53.3
N.A.
N.A.
20
46.6
53.3
P-Site Similarity:
100
100
100
20
N.A.
73.3
N.A.
N.A.
73.3
N.A.
80
80
N.A.
N.A.
33.3
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
28
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% C
% Asp:
0
0
0
64
0
0
0
0
0
0
0
0
0
19
0
% D
% Glu:
10
0
0
28
0
0
10
0
0
0
0
0
0
73
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% G
% His:
28
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
55
0
0
10
0
0
0
% I
% Lys:
10
10
55
0
46
37
10
10
0
0
0
0
0
0
0
% K
% Leu:
0
28
0
0
0
0
73
0
0
0
0
0
0
10
82
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
46
28
0
28
55
0
0
0
28
0
0
82
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% S
% Thr:
37
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
10
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
73
0
0
10
91
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _