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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21A
All Species:
25.45
Human Site:
Y132
Identified Species:
56
UniProt:
Q8NDW8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDW8
NP_001098983.1
1320
150944
Y132
R
H
D
K
A
K
E
Y
I
D
R
M
L
K
I
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
Y132
R
H
D
K
A
K
E
Y
I
D
R
M
L
K
I
Rhesus Macaque
Macaca mulatta
XP_001083557
1313
149854
Y132
H
H
D
K
A
K
E
Y
I
D
R
M
L
K
I
Dog
Lupus familis
XP_542714
1222
139067
Y129
H
Y
D
K
A
R
E
Y
I
D
C
N
L
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0S4
1314
148598
Y132
H
H
D
K
A
R
E
Y
V
D
H
M
L
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
Y130
R
H
D
K
A
R
E
Y
V
D
R
M
I
K
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC1
1312
148653
R130
M
G
R
T
D
K
A
R
E
Y
I
D
R
M
L
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
Y135
R
N
D
K
A
R
E
Y
V
D
R
M
I
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
N130
V
L
E
Q
D
P
K
N
V
N
A
L
L
G
F
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
K149
Y
F
A
G
E
Y
Q
K
S
K
Q
M
L
D
I
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
A129
H
T
G
R
H
D
K
A
R
E
Y
V
D
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.7
76.2
N.A.
76.6
N.A.
N.A.
49.2
N.A.
59.7
51.6
N.A.
N.A.
28.8
29
47.4
Protein Similarity:
100
99.8
98.3
83.1
N.A.
86.5
N.A.
N.A.
68.9
N.A.
75
72.2
N.A.
N.A.
47.7
49.7
68.7
P-Site Identity:
100
100
93.3
60
N.A.
66.6
N.A.
N.A.
80
N.A.
6.6
73.3
N.A.
N.A.
6.6
20
0
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
N.A.
N.A.
100
N.A.
13.3
100
N.A.
N.A.
46.6
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
64
0
10
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
64
0
19
10
0
0
0
64
0
10
10
10
0
% D
% Glu:
0
0
10
0
10
0
64
0
10
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
10
10
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
37
46
0
0
10
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
37
0
10
0
19
0
55
% I
% Lys:
0
0
0
64
0
37
19
10
0
10
0
0
0
64
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
10
64
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
64
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
37
0
10
10
0
37
0
10
10
0
46
0
10
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% S
% Thr:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
37
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
10
0
64
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _