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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC21A
All Species:
26.67
Human Site:
S522
Identified Species:
58.67
UniProt:
Q8NDW8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDW8
NP_001098983.1
1320
150944
S522
S
E
L
E
N
A
Q
S
I
L
Q
R
C
L
E
Chimpanzee
Pan troglodytes
XP_516376
1320
150978
S522
S
E
L
E
N
A
Q
S
I
L
Q
R
C
L
E
Rhesus Macaque
Macaca mulatta
XP_001083557
1313
149854
S515
G
E
L
E
N
A
Q
S
I
L
Q
R
C
L
E
Dog
Lupus familis
XP_542714
1222
139067
S521
S
E
L
E
N
A
Q
S
T
L
Q
R
C
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0S4
1314
148598
S515
G
E
L
E
N
A
Q
S
T
L
Q
R
C
L
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513615
1329
151533
S513
G
D
A
A
A
A
S
S
N
L
K
H
C
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6INC1
1312
148653
G514
G
N
L
E
G
A
Q
G
S
L
Q
R
C
I
E
Zebra Danio
Brachydanio rerio
NP_001121730
1321
150895
S518
G
D
I
D
A
A
Q
S
S
L
Q
H
C
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396105
1491
170258
S518
M
S
Y
A
G
M
Q
S
Y
K
S
N
L
E
I
Nematode Worm
Caenorhab. elegans
Q20255
1332
152170
K531
S
N
T
N
A
A
E
K
W
I
E
K
V
L
D
Sea Urchin
Strong. purpuratus
XP_793431
1316
149470
T514
G
Q
V
E
Q
A
Q
T
S
L
Q
H
C
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.7
76.2
N.A.
76.6
N.A.
N.A.
49.2
N.A.
59.7
51.6
N.A.
N.A.
28.8
29
47.4
Protein Similarity:
100
99.8
98.3
83.1
N.A.
86.5
N.A.
N.A.
68.9
N.A.
75
72.2
N.A.
N.A.
47.7
49.7
68.7
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
N.A.
N.A.
40
N.A.
60
46.6
N.A.
N.A.
13.3
20
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
N.A.
N.A.
53.3
N.A.
66.6
73.3
N.A.
N.A.
13.3
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
19
28
91
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% C
% Asp:
0
19
0
10
0
0
0
0
0
0
0
0
0
0
28
% D
% Glu:
0
46
0
64
0
0
10
0
0
0
10
0
0
10
64
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
0
0
0
19
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
28
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
28
10
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
10
10
0
0
0
% K
% Leu:
0
0
55
0
0
0
0
0
0
82
0
0
10
82
0
% L
% Met:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
10
46
0
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
10
0
82
0
0
0
73
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% R
% Ser:
37
10
0
0
0
0
10
73
28
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
10
19
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _