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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
20.91
Human Site:
Y731
Identified Species:
30.67
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
Y731
K
K
H
L
V
A
F
Y
Q
E
Q
S
Q
L
Q
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
Y731
K
K
H
L
V
A
F
Y
Q
E
Q
S
Q
L
Q
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
Y731
K
K
H
L
V
A
F
Y
R
E
Q
S
Q
L
Q
Dog
Lupus familis
XP_538328
1235
143711
Y731
K
K
Q
L
A
A
F
Y
R
E
Q
S
Q
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
Y731
K
K
H
L
A
T
F
Y
R
E
Q
S
Q
L
Q
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
L731
T
R
H
L
A
L
N
L
Q
E
K
S
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
Y702
K
K
H
L
A
N
F
Y
K
E
Q
S
Q
L
E
Chicken
Gallus gallus
Q90988
1189
134923
K749
Q
E
D
L
L
A
L
K
K
T
I
A
E
C
E
Frog
Xenopus laevis
O93308
1232
142609
M731
T
R
H
L
A
M
N
M
Q
E
K
S
K
L
E
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
Q733
K
K
S
I
P
A
A
Q
I
E
I
S
K
L
R
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
F739
K
K
N
L
A
G
L
F
Q
E
I
S
R
L
E
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
D756
K
K
S
I
S
Q
Y
D
N
Q
L
Q
Q
V
Q
Honey Bee
Apis mellifera
XP_395059
1230
141414
E735
Q
K
Q
I
A
E
L
E
T
E
L
D
A
L
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
D733
K
K
I
L
A
N
N
D
K
A
I
Q
K
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
N774
Q
R
E
I
E
S
L
N
S
E
H
N
Y
L
E
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
Q757
D
L
I
E
K
E
I
Q
P
K
I
T
E
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
93.3
80
N.A.
80
40
N.A.
73.3
13.3
40
40
46.6
26.6
26.6
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
66.6
N.A.
86.6
60
66.6
60
73.3
53.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
38
7
0
0
7
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
7
0
7
0
0
0
0
13
0
0
0
7
0
0
0
% D
% Glu:
0
7
7
7
7
13
0
7
0
75
0
0
13
0
38
% E
% Phe:
0
0
0
0
0
0
38
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
44
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
13
25
0
0
7
0
7
0
32
0
0
0
0
% I
% Lys:
63
69
0
0
7
0
0
7
19
7
13
0
25
0
7
% K
% Leu:
0
7
0
69
7
7
25
7
0
0
13
0
0
88
0
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
13
19
7
7
0
0
7
0
0
7
% N
% Pro:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
19
0
13
0
0
7
0
13
32
7
38
13
44
0
44
% Q
% Arg:
0
19
0
0
0
0
0
0
19
0
0
0
7
0
7
% R
% Ser:
0
0
13
0
7
7
0
0
7
0
0
63
0
0
0
% S
% Thr:
13
0
0
0
0
7
0
0
7
7
0
7
0
0
0
% T
% Val:
0
0
0
0
19
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
38
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _