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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
43.33
Human Site:
Y168
Identified Species:
63.56
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
Y168
S
G
E
L
I
G
E
Y
E
E
K
K
R
K
L
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
Y168
S
G
E
L
I
G
E
Y
E
E
K
K
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
Y168
S
G
E
L
I
G
E
Y
E
E
K
K
R
K
L
Dog
Lupus familis
XP_538328
1235
143711
Y168
S
G
E
L
I
G
E
Y
E
E
K
K
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
Y168
S
G
E
F
I
G
E
Y
E
A
K
K
K
K
L
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
Y168
S
G
E
L
A
Q
E
Y
D
K
R
K
K
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
A165
N
K
K
K
N
V
A
A
E
R
K
H
A
K
L
Chicken
Gallus gallus
Q90988
1189
134923
K178
T
R
M
Y
E
C
K
K
I
T
A
H
K
T
I
Frog
Xenopus laevis
O93308
1232
142609
Y168
S
G
E
L
A
Q
E
Y
D
K
R
K
K
E
M
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
Y168
S
G
D
L
N
I
E
Y
F
T
K
L
A
V
L
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
Y168
S
K
E
L
A
A
E
Y
I
R
R
K
E
A
L
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
Y191
S
G
L
L
K
D
D
Y
N
R
L
K
Q
E
M
Honey Bee
Apis mellifera
XP_395059
1230
141414
Y169
S
G
A
L
K
A
E
Y
E
R
L
R
T
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
Y168
S
G
E
L
R
E
E
Y
E
Q
R
K
A
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
T202
Y
L
E
D
I
I
G
T
N
K
Y
V
E
K
I
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
Y182
S
I
Q
Y
K
K
E
Y
E
E
L
K
E
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
100
100
N.A.
80
46.6
N.A.
26.6
0
46.6
46.6
46.6
33.3
40
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
40
26.6
86.6
53.3
53.3
60
60
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
19
13
7
7
0
7
7
0
19
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
7
7
0
13
0
0
0
0
0
0
% D
% Glu:
0
0
63
0
7
7
75
0
57
32
0
0
19
25
0
% E
% Phe:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
69
0
0
0
32
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% H
% Ile:
0
7
0
0
38
13
0
0
13
0
0
0
0
0
19
% I
% Lys:
0
13
7
7
19
7
7
7
0
19
44
69
25
50
0
% K
% Leu:
0
7
7
69
0
0
0
0
0
0
19
7
0
0
50
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
32
% M
% Asn:
7
0
0
0
13
0
0
0
13
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
13
0
0
0
7
0
0
7
0
0
% Q
% Arg:
0
7
0
0
7
0
0
0
0
25
25
7
25
0
0
% R
% Ser:
82
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
7
0
13
0
0
7
7
0
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
13
0
0
0
82
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _