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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
25.45
Human Site:
Y1063
Identified Species:
37.33
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
Y1063
E
Q
V
K
K
R
R
Y
D
L
F
T
Q
C
F
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
Y1063
E
Q
V
K
K
R
R
Y
D
L
F
T
Q
C
F
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
Y1063
E
Q
V
K
K
R
R
Y
D
L
F
T
Q
C
F
Dog
Lupus familis
XP_538328
1235
143711
Y1063
E
Q
V
K
K
R
R
Y
D
L
F
S
Q
C
F
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
Y1062
E
Q
V
K
R
R
R
Y
D
A
F
S
Q
C
F
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
F1067
E
Q
I
K
K
E
R
F
D
R
F
N
A
C
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
Y1034
E
Q
V
K
K
R
R
Y
D
L
F
S
Q
C
F
Chicken
Gallus gallus
Q90988
1189
134923
K1025
T
I
E
E
L
D
R
K
K
N
K
A
L
H
I
Frog
Xenopus laevis
O93308
1232
142609
F1067
E
Q
T
K
K
E
R
F
D
R
F
N
A
C
F
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
F1065
E
Q
V
K
A
K
R
F
H
L
F
S
Q
C
F
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
C1070
E
Q
V
K
F
Q
R
C
Q
R
F
N
K
C
F
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
A1065
F
E
N
A
R
K
K
A
K
R
A
K
A
A
F
Honey Bee
Apis mellifera
XP_395059
1230
141414
K1066
T
Q
F
E
K
I
K
K
E
R
H
D
R
F
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
Y1077
E
I
I
R
K
E
R
Y
E
R
F
N
T
C
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
E1052
A
E
Y
R
S
K
V
E
L
Y
N
G
R
V
D
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
K1061
L
K
I
K
K
K
R
K
E
L
F
E
K
T
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
100
93.3
N.A.
80
60
N.A.
93.3
6.6
60
66.6
53.3
6.6
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
73.3
N.A.
100
13.3
66.6
86.6
66.6
33.3
40
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
0
0
7
0
7
7
7
19
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
69
0
% C
% Asp:
0
0
0
0
0
7
0
0
50
0
0
7
0
0
7
% D
% Glu:
69
13
7
13
0
19
0
7
19
0
0
7
0
0
0
% E
% Phe:
7
0
7
0
7
0
0
19
0
0
75
0
0
7
82
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
7
0
0
7
0
% H
% Ile:
0
13
19
0
0
7
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
7
0
69
63
25
13
19
13
0
7
7
13
0
0
% K
% Leu:
7
0
0
0
7
0
0
0
7
44
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
0
0
0
0
0
0
7
7
25
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
69
0
0
0
7
0
0
7
0
0
0
44
0
0
% Q
% Arg:
0
0
0
13
13
38
82
0
0
38
0
0
13
0
0
% R
% Ser:
0
0
0
0
7
0
0
0
0
0
0
25
0
0
0
% S
% Thr:
13
0
7
0
0
0
0
0
0
0
0
19
7
7
0
% T
% Val:
0
0
50
0
0
0
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
44
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _