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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
39.7
Human Site:
T962
Identified Species:
58.22
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
T962
M
G
T
E
A
E
S
T
Q
A
T
I
D
I
Y
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
T962
M
G
T
E
A
E
S
T
Q
A
T
I
D
I
Y
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
T962
M
G
T
E
A
E
S
T
Q
A
T
I
D
I
Y
Dog
Lupus familis
XP_538328
1235
143711
T962
L
G
T
E
A
E
S
T
Q
A
T
V
D
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
T961
E
L
T
E
T
E
S
T
Q
A
T
A
D
I
Y
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S966
G
E
E
S
V
S
G
S
Q
R
T
S
S
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
T933
P
G
T
E
P
E
S
T
Q
A
T
S
V
I
F
Chicken
Gallus gallus
Q90988
1189
134923
T930
E
T
A
D
A
S
S
T
L
D
K
L
L
K
E
Frog
Xenopus laevis
O93308
1232
142609
S966
G
E
E
S
A
S
S
S
Q
R
S
S
T
V
Y
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
S964
V
Q
T
E
E
S
Q
S
V
S
T
L
D
I
F
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
T969
Q
V
T
E
T
E
S
T
L
G
T
L
D
L
Y
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
I961
L
Q
A
K
T
D
C
I
V
V
P
L
L
R
G
Honey Bee
Apis mellifera
XP_395059
1230
141414
S969
S
D
T
N
N
D
S
S
L
N
T
Q
Q
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S977
T
G
A
D
S
M
S
S
Q
G
A
K
S
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
S952
S
V
D
E
L
K
A
S
R
V
D
A
E
F
K
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
T958
I
P
I
S
S
E
T
T
I
D
D
L
P
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
100
86.6
N.A.
73.3
26.6
N.A.
66.6
20
26.6
33.3
53.3
0
26.6
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
33.3
N.A.
73.3
33.3
46.6
66.6
66.6
26.6
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
38
0
7
0
0
38
7
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
13
0
13
0
0
0
13
13
0
44
0
0
% D
% Glu:
13
13
13
57
7
50
0
0
0
0
0
0
7
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
13
% F
% Gly:
13
38
0
0
0
0
7
0
0
13
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
7
7
0
0
19
0
63
0
% I
% Lys:
0
0
0
7
0
7
0
0
0
0
7
7
0
7
7
% K
% Leu:
13
7
0
0
7
0
0
0
19
0
0
32
13
7
0
% L
% Met:
19
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
7
7
0
0
7
0
0
0
0
0
7
0
7
0
0
% P
% Gln:
7
13
0
0
0
0
7
0
57
0
0
7
7
7
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
13
0
0
0
7
0
% R
% Ser:
13
0
0
19
13
25
69
38
0
7
7
19
13
0
7
% S
% Thr:
7
7
57
0
19
0
7
57
0
0
63
0
7
0
0
% T
% Val:
7
13
0
0
7
0
0
0
13
13
0
7
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
63
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _