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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
11.21
Human Site:
T862
Identified Species:
16.44
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
T862
A
E
E
N
C
L
Q
T
V
N
E
L
M
A
K
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
T862
A
E
E
N
C
L
Q
T
V
N
E
L
M
A
K
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
I862
A
E
E
N
C
L
Q
I
V
N
E
L
M
A
K
Dog
Lupus familis
XP_538328
1235
143711
I862
V
E
E
D
C
L
Q
I
V
N
E
L
M
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
I862
T
E
E
E
C
L
K
I
V
E
E
L
M
V
K
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
I862
E
E
Q
R
H
M
K
I
I
D
E
T
M
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
F833
A
E
K
K
C
L
Q
F
V
E
E
V
K
V
Q
Chicken
Gallus gallus
Q90988
1189
134923
S849
A
A
Q
Q
A
I
A
S
L
K
E
Q
V
S
A
Frog
Xenopus laevis
O93308
1232
142609
I862
E
E
Q
R
H
M
K
I
I
D
E
T
M
A
Q
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
A864
G
E
D
N
I
L
I
A
V
E
Q
T
Q
S
N
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
D870
G
E
K
K
L
L
L
D
V
E
E
A
Q
N
K
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
G874
D
E
E
D
A
L
E
G
L
K
L
A
E
A
R
Honey Bee
Apis mellifera
XP_395059
1230
141414
T857
K
L
E
S
A
R
Q
T
E
S
N
Q
K
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
I862
E
E
A
K
Q
M
K
I
I
D
D
E
T
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
T871
R
C
N
V
Q
I
E
T
N
Q
K
L
I
K
K
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
I870
L
E
E
Q
E
Y
A
I
E
M
K
I
G
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
93.3
80
N.A.
60
26.6
N.A.
46.6
13.3
26.6
26.6
33.3
26.6
26.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
66.6
66.6
N.A.
66.6
53.3
66.6
46.6
40
53.3
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
32
7
7
0
19
0
13
7
0
0
0
13
0
50
7
% A
% Cys:
0
7
0
0
38
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
13
0
0
0
7
0
19
7
0
0
0
0
% D
% Glu:
19
82
50
7
7
0
13
0
13
25
63
7
7
7
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
13
7
44
19
0
0
7
7
0
7
% I
% Lys:
7
0
13
19
0
0
25
0
0
13
13
0
13
7
44
% K
% Leu:
7
7
0
0
7
57
7
0
13
0
7
38
0
0
0
% L
% Met:
0
0
0
0
0
19
0
0
0
7
0
0
44
0
0
% M
% Asn:
0
0
7
25
0
0
0
0
7
25
7
0
0
7
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
19
13
13
0
38
0
0
7
7
13
13
0
19
% Q
% Arg:
7
0
0
13
0
7
0
0
0
0
0
0
0
0
7
% R
% Ser:
0
0
0
7
0
0
0
7
0
7
0
0
0
19
7
% S
% Thr:
7
0
0
0
0
0
0
25
0
0
0
19
7
0
0
% T
% Val:
7
0
0
7
0
0
0
0
50
0
0
7
7
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _