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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
20
Human Site:
T1222
Identified Species:
29.33
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
T1222
D
L
S
Q
Y
P
D
T
E
G
Q
E
S
S
K
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
T1222
D
L
S
Q
Y
P
D
T
E
G
Q
E
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
T1222
D
L
S
Q
Y
P
D
T
E
G
Q
E
S
K
R
Dog
Lupus familis
XP_538328
1235
143711
N1222
D
L
S
Q
Y
P
D
N
E
D
R
E
N
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
T1221
D
L
S
K
Y
P
D
T
E
D
Q
E
G
S
R
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T1221
K
V
L
T
F
D
L
T
K
Y
P
D
A
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
S1193
D
L
T
L
Y
P
E
S
E
A
S
E
G
S
R
Chicken
Gallus gallus
Q90988
1189
134923
K1177
R
H
C
Q
L
K
K
K
Q
P
L
S
E
A
S
Frog
Xenopus laevis
O93308
1232
142609
L1220
S
K
V
L
T
F
D
L
T
K
Y
P
D
A
N
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
L1223
L
D
L
T
P
Y
P
L
K
D
E
N
A
T
D
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
A1229
D
L
R
P
Y
P
L
A
E
E
A
R
E
K
Q
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
C1222
I
T
P
G
E
G
D
C
L
V
S
N
V
Y
I
Honey Bee
Apis mellifera
XP_395059
1230
141414
T1218
C
L
E
S
K
V
L
T
L
D
L
T
T
Y
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
E1232
V
L
T
L
D
L
T
E
Y
P
E
A
P
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L1209
L
R
N
N
M
F
E
L
A
D
R
L
V
G
I
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
S1213
R
Q
Q
Q
E
N
S
S
K
I
I
T
L
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
86.6
73.3
N.A.
73.3
6.6
N.A.
46.6
6.6
6.6
0
33.3
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
46.6
N.A.
73.3
20
13.3
26.6
40
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
7
7
7
7
13
19
0
% A
% Cys:
7
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
44
7
0
0
7
7
44
0
0
32
0
7
7
7
7
% D
% Glu:
0
0
7
0
13
0
13
7
44
7
13
38
13
0
0
% E
% Phe:
0
0
0
0
7
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
7
0
0
0
19
0
0
13
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
7
7
0
0
0
19
% I
% Lys:
7
7
0
7
7
7
7
7
19
7
0
0
0
13
19
% K
% Leu:
13
57
13
19
7
7
19
19
13
0
13
7
7
0
7
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
7
0
7
0
0
0
13
7
7
7
% N
% Pro:
0
0
7
7
7
44
7
0
0
13
7
7
7
0
13
% P
% Gln:
0
7
7
38
0
0
0
0
7
0
25
0
0
0
7
% Q
% Arg:
13
7
7
0
0
0
0
0
0
0
13
7
0
0
19
% R
% Ser:
7
0
32
7
0
0
7
13
0
0
13
7
19
32
7
% S
% Thr:
0
7
13
13
7
0
7
38
7
0
0
13
7
7
0
% T
% Val:
7
7
7
0
0
7
0
0
0
7
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
44
7
0
0
7
7
7
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _