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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
18.48
Human Site:
S471
Identified Species:
27.11
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S471
E
K
T
K
S
R
M
S
E
F
N
E
E
L
N
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S471
E
K
T
K
S
R
M
S
E
V
N
E
E
L
N
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S471
E
K
T
K
S
R
I
S
E
V
N
E
E
L
N
Dog
Lupus familis
XP_538328
1235
143711
S471
E
N
T
K
S
R
M
S
E
V
N
E
E
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S471
E
N
T
K
S
R
M
S
E
V
N
E
E
L
S
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
D471
E
M
A
K
R
R
I
D
E
I
N
K
E
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
A442
E
N
S
K
L
R
M
A
E
V
N
E
E
L
N
Chicken
Gallus gallus
Q90988
1189
134923
E476
K
Y
E
E
A
E
Q
E
A
H
L
A
K
K
K
Frog
Xenopus laevis
O93308
1232
142609
D471
E
M
A
K
R
R
I
D
E
I
N
S
E
L
N
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
E471
A
K
G
L
V
R
M
E
E
V
N
V
E
L
A
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
E475
E
R
G
R
Q
R
S
E
K
V
A
Q
E
L
S
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
A494
G
T
S
K
E
K
I
A
E
K
Q
R
E
L
E
Honey Bee
Apis mellifera
XP_395059
1230
141414
Q472
G
T
S
K
D
K
I
Q
N
L
Q
R
E
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
Q471
M
G
A
S
S
R
M
Q
E
I
E
T
E
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L514
S
L
K
E
Q
E
T
L
V
P
Q
E
Q
A
A
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
Y486
E
S
A
N
N
Q
E
Y
D
L
N
F
K
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
93.3
86.6
86.6
N.A.
80
53.3
N.A.
66.6
0
53.3
46.6
26.6
26.6
20
N.A.
33.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
86.6
66.6
N.A.
80
26.6
60
46.6
60
53.3
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
25
0
7
0
0
13
7
0
7
7
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
13
7
0
0
0
0
0
0
% D
% Glu:
63
0
7
13
7
13
7
19
69
0
7
44
82
0
13
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
13
7
13
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
32
0
0
19
0
0
0
0
0
% I
% Lys:
7
25
7
63
0
13
0
0
7
7
0
7
13
7
7
% K
% Leu:
0
7
0
7
7
0
0
7
0
13
7
0
0
82
0
% L
% Met:
7
13
0
0
0
0
44
0
0
0
0
0
0
7
0
% M
% Asn:
0
19
0
7
7
0
0
0
7
0
63
0
0
0
44
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
7
7
13
0
0
19
7
7
0
0
% Q
% Arg:
0
7
0
7
13
69
0
0
0
0
0
13
0
0
7
% R
% Ser:
7
7
19
7
38
0
7
32
0
0
0
7
0
0
13
% S
% Thr:
0
13
32
0
0
0
7
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
7
44
0
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _