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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
13.64
Human Site:
S322
Identified Species:
20
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S322
A
K
K
S
I
K
D
S
E
K
Q
C
S
K
Q
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S322
A
K
K
S
I
K
D
S
E
K
Q
C
S
K
Q
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S322
A
K
K
T
I
K
D
S
E
K
Q
C
S
K
Q
Dog
Lupus familis
XP_538328
1235
143711
S322
A
K
K
S
I
K
D
S
E
K
Q
C
S
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
N322
S
K
K
L
I
T
D
N
E
K
Q
C
S
K
Q
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
R322
A
K
K
S
L
Q
N
R
Q
K
H
Y
K
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
A293
E
S
E
G
I
R
E
A
E
E
Q
C
A
K
Q
Chicken
Gallus gallus
Q90988
1189
134923
H319
K
V
R
S
D
L
D
H
R
K
Q
N
L
N
S
Frog
Xenopus laevis
O93308
1232
142609
A322
A
K
K
S
L
Q
N
A
Q
K
Q
Y
K
K
R
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
N322
A
H
R
S
L
Q
K
N
Q
N
L
Q
A
K
K
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
A322
A
R
D
A
L
K
K
A
E
K
T
S
V
T
K
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
A345
L
Q
K
T
L
E
T
A
R
E
A
D
N
A
H
Honey Bee
Apis mellifera
XP_395059
1230
141414
A323
A
R
K
S
L
A
Q
A
R
I
A
D
E
A
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
A322
A
K
K
S
L
K
S
A
K
K
A
H
E
K
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
K359
K
I
K
K
L
E
D
K
L
E
K
D
S
S
K
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
L336
I
E
K
R
I
E
S
L
Q
K
D
L
Q
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
100
93.3
100
N.A.
73.3
40
N.A.
40
26.6
46.6
20
26.6
6.6
20
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
73.3
N.A.
80
33.3
86.6
66.6
60
53.3
40
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
63
0
0
7
0
7
0
38
0
0
19
0
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
38
0
0
0
% C
% Asp:
0
0
7
0
7
0
44
0
0
0
7
19
0
0
0
% D
% Glu:
7
7
7
0
0
19
7
0
44
19
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
0
0
0
7
0
0
7
7
0
0
19
% H
% Ile:
7
7
0
0
44
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
13
50
75
7
0
38
13
7
7
69
7
0
13
63
19
% K
% Leu:
7
0
0
7
50
7
0
7
7
0
7
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
13
0
7
0
7
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
19
7
0
25
0
50
7
7
0
44
% Q
% Arg:
0
13
13
7
0
7
0
7
19
0
0
0
0
7
13
% R
% Ser:
7
7
0
57
0
0
13
25
0
0
0
7
38
7
7
% S
% Thr:
0
0
0
13
0
7
7
0
0
0
7
0
0
7
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _