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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1B
All Species:
40.91
Human Site:
S159
Identified Species:
60
UniProt:
Q8NDV3
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDV3
NP_683515.3
1235
143908
S159
T
Q
F
F
E
E
I
S
T
S
G
E
L
I
G
Chimpanzee
Pan troglodytes
XP_001135642
1235
143837
S159
T
Q
F
F
E
E
I
S
S
S
G
E
L
I
G
Rhesus Macaque
Macaca mulatta
XP_001109647
1234
143862
S159
T
Q
F
F
E
E
I
S
T
S
G
E
L
I
G
Dog
Lupus familis
XP_538328
1235
143711
S159
T
Q
F
F
E
E
I
S
T
S
G
E
L
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q920F6
1248
144495
S159
T
Q
F
F
E
E
I
S
T
S
G
E
F
I
G
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S159
T
A
L
F
E
E
I
S
R
S
G
E
L
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
N156
A
E
E
D
A
Q
F
N
F
N
K
K
K
N
V
Chicken
Gallus gallus
Q90988
1189
134923
A169
L
A
M
I
E
E
A
A
G
T
R
M
Y
E
C
Frog
Xenopus laevis
O93308
1232
142609
S159
T
A
L
F
E
E
I
S
R
S
G
E
L
A
Q
Zebra Danio
Brachydanio rerio
XP_001334257
1235
141752
S159
T
K
M
F
E
R
I
S
G
S
G
D
L
N
I
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
S159
T
K
M
F
E
S
I
S
Q
S
K
E
L
A
A
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
S182
T
A
L
F
E
E
I
S
G
S
G
L
L
K
D
Honey Bee
Apis mellifera
XP_395059
1230
141414
S160
T
A
L
F
E
E
I
S
N
S
G
A
L
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S159
T
A
L
F
E
E
I
S
R
S
G
E
L
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L193
G
P
H
D
E
G
F
L
E
Y
L
E
D
I
I
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
S173
S
R
M
F
E
E
V
S
G
S
I
Q
Y
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95
89.5
N.A.
82.1
53.1
N.A.
66.6
22.7
53.1
52.7
50.1
40
43
N.A.
48.6
Protein Similarity:
100
99.6
97.2
95.1
N.A.
90.8
74.6
N.A.
78.7
44.3
73.5
72
71.4
62.5
65.5
N.A.
68.3
P-Site Identity:
100
93.3
100
100
N.A.
93.3
66.6
N.A.
0
13.3
66.6
53.3
53.3
60
60
N.A.
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
66.6
N.A.
33.3
26.6
66.6
66.6
60
60
60
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
28.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.3
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
38
0
0
7
0
7
7
0
0
0
7
0
19
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
13
0
0
0
0
0
0
0
7
7
0
7
% D
% Glu:
0
7
7
0
94
75
0
0
7
0
0
63
0
7
7
% E
% Phe:
0
0
32
82
0
0
13
0
7
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
0
7
0
0
25
0
69
0
0
0
32
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
75
0
0
0
7
0
0
38
13
% I
% Lys:
0
13
0
0
0
0
0
0
0
0
13
7
7
19
7
% K
% Leu:
7
0
32
0
0
0
0
7
0
0
7
7
69
0
0
% L
% Met:
0
0
25
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
7
7
0
0
0
13
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
32
0
0
0
7
0
0
7
0
0
7
0
0
13
% Q
% Arg:
0
7
0
0
0
7
0
0
19
0
7
0
0
7
0
% R
% Ser:
7
0
0
0
0
7
0
82
7
82
0
0
0
0
0
% S
% Thr:
75
0
0
0
0
0
0
0
25
7
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _