Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMC1B All Species: 10.62
Human Site: S1234 Identified Species: 15.57
UniProt: Q8NDV3 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NDV3 NP_683515.3 1235 143908 S1234 S S K R H G E S R _ _ _ _ _ _
Chimpanzee Pan troglodytes XP_001135642 1235 143837 S1234 S S K R H G E S R _ _ _ _ _ _
Rhesus Macaque Macaca mulatta XP_001109647 1234 143862
Dog Lupus familis XP_538328 1235 143711 S1234 N S K R N H E S R _ _ _ _ _ _
Cat Felis silvestris
Mouse Mus musculus Q920F6 1248 144495 P1233 G S R S H R K P R V P R V S M
Rat Rattus norvegicus Q9Z1M9 1233 143186
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511311 1329 152821 A1205 G S R S S C R A G N G Q S L V
Chicken Gallus gallus Q90988 1189 134923
Frog Xenopus laevis O93308 1232 142609
Zebra Danio Brachydanio rerio XP_001334257 1235 141752
Tiger Blowfish Takifugu rubipres NP_001027867 1245 142913 R1241 E K Q A H V E R V R P V _ _ _
Fruit Fly Dros. melanogaster NP_651211 1238 142862 T1234 V Y I M D L T T F E D T _ _ _
Honey Bee Apis mellifera XP_395059 1230 141414
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786064 1247 143265 T1244 P A I P N P I T G I R _ _ _ _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJL0 1241 141112 N1221 V G I Y K T D N C T K S I T I
Baker's Yeast Sacchar. cerevisiae P32908 1225 141262
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95 89.5 N.A. 82.1 53.1 N.A. 66.6 22.7 53.1 52.7 50.1 40 43 N.A. 48.6
Protein Similarity: 100 99.6 97.2 95.1 N.A. 90.8 74.6 N.A. 78.7 44.3 73.5 72 71.4 62.5 65.5 N.A. 68.3
P-Site Identity: 100 100 0 66.6 N.A. 20 0 N.A. 6.6 0 0 0 16.6 0 0 N.A. 0
P-Site Similarity: 100 100 0 88.8 N.A. 33.3 0 N.A. 26.6 0 0 0 25 8.3 0 N.A. 36.3
Percent
Protein Identity: N.A. N.A. N.A. 24.1 28.1 N.A.
Protein Similarity: N.A. N.A. N.A. 47.3 53.2 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 0 0 7 0 0 0 0 % D
% Glu: 7 0 0 0 0 0 25 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 13 7 0 0 0 13 0 0 13 0 7 0 0 0 0 % G
% His: 0 0 0 0 25 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 19 0 0 0 7 0 0 7 0 0 7 0 7 % I
% Lys: 0 7 19 0 7 0 7 0 0 0 7 0 0 0 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 0 0 0 13 0 0 7 0 7 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 7 0 7 0 0 13 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 13 19 0 7 7 7 25 7 7 7 0 0 0 % R
% Ser: 13 32 0 13 7 0 0 19 0 0 0 7 7 7 0 % S
% Thr: 0 0 0 0 0 7 7 13 0 7 0 7 0 7 0 % T
% Val: 13 0 0 0 0 7 0 0 7 7 0 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 19 19 25 38 38 38 % _