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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
21.82
Human Site:
Y255
Identified Species:
43.64
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
Y255
A
C
I
G
F
H
P
Y
D
F
V
A
L
K
Q
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
Y255
A
C
I
G
F
H
P
Y
D
F
V
A
L
K
Q
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
P249
E
S
F
K
G
Y
Q
P
Y
E
F
T
T
L
K
Dog
Lupus familis
XP_545600
481
53856
Y255
A
C
T
G
F
R
P
Y
D
F
V
A
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
K208
L
K
K
D
V
C
Q
K
V
D
L
L
G
A
S
Rat
Rattus norvegicus
Q6RUG5
435
48626
L211
D
V
C
Q
K
V
D
L
L
G
A
S
R
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
Y255
E
F
T
E
V
H
P
Y
D
F
V
V
L
K
R
Chicken
Gallus gallus
XP_418682
516
58625
Y264
S
F
K
G
Y
Q
P
Y
E
F
T
M
L
K
S
Frog
Xenopus laevis
NP_001080094
512
57900
Y264
S
F
K
G
Y
Q
P
Y
E
F
T
T
L
K
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
Y272
S
F
K
G
Y
Q
R
Y
D
F
M
V
V
K
E
Nematode Worm
Caenorhab. elegans
P91124
430
48887
N207
A
Q
T
T
V
K
S
N
K
E
R
L
D
R
L
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
Y370
G
F
R
G
Y
Q
H
Y
E
F
N
M
L
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
0
86.6
N.A.
0
0
N.A.
53.3
40
40
N.A.
N.A.
N.A.
33.3
6.6
33.3
P-Site Similarity:
100
100
13.3
86.6
N.A.
6.6
6.6
N.A.
60
60
60
N.A.
N.A.
N.A.
66.6
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
0
0
0
9
25
0
9
0
% A
% Cys:
0
25
9
0
0
9
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
0
0
9
0
0
9
0
42
9
0
0
9
0
0
% D
% Glu:
17
0
0
9
0
0
0
0
25
17
0
0
0
0
9
% E
% Phe:
0
42
9
0
25
0
0
0
0
67
9
0
0
0
0
% F
% Gly:
9
0
0
59
9
0
0
0
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
25
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
34
9
9
9
0
9
9
0
0
0
0
67
9
% K
% Leu:
9
0
0
0
0
0
0
9
9
0
9
17
59
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
17
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
50
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
9
0
34
17
0
0
0
0
0
0
0
25
% Q
% Arg:
0
0
9
0
0
9
9
0
0
0
9
0
9
9
9
% R
% Ser:
25
9
0
0
0
0
9
0
0
0
0
9
0
0
25
% S
% Thr:
0
0
25
9
0
0
0
0
0
0
17
17
9
0
0
% T
% Val:
0
9
0
0
25
9
0
0
9
0
34
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
34
9
0
67
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _