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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
8.79
Human Site:
S438
Identified Species:
17.58
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
S438
N
Q
P
V
P
S
Q
S
P
K
K
L
T
R
S
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
S437
N
Q
P
V
P
S
Q
S
P
K
K
L
T
R
S
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
A429
Q
N
M
K
D
L
Q
A
S
L
Q
E
P
A
K
Dog
Lupus familis
XP_545600
481
53856
S437
D
Q
P
V
P
S
Q
S
T
K
K
L
T
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
A388
L
F
D
L
G
L
H
A
D
G
A
F
N
T
P
Rat
Rattus norvegicus
Q6RUG5
435
48626
W391
A
D
G
A
F
N
S
W
A
S
Q
E
G
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
F437
N
Q
S
H
P
M
L
F
Y
L
L
L
L
A
A
Chicken
Gallus gallus
XP_418682
516
58625
N470
N
S
L
N
V
N
A
N
K
T
P
M
K
G
E
Frog
Xenopus laevis
NP_001080094
512
57900
K466
S
S
N
P
S
T
N
K
A
P
A
K
D
V
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
K495
A
A
L
G
I
G
Q
K
N
M
L
T
T
I
N
Nematode Worm
Caenorhab. elegans
P91124
430
48887
V387
P
P
P
K
P
N
A
V
S
D
D
I
L
S
L
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
D644
P
A
G
A
N
K
T
D
S
S
K
P
Q
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
6.6
80
N.A.
0
0
N.A.
26.6
6.6
6.6
N.A.
N.A.
N.A.
13.3
13.3
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
13.3
13.3
N.A.
33.3
26.6
20
N.A.
N.A.
N.A.
20
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
0
17
0
0
17
17
17
0
17
0
0
25
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
9
0
0
9
9
9
9
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
17
% E
% Phe:
0
9
0
0
9
0
0
9
0
0
0
9
0
0
9
% F
% Gly:
0
0
17
9
9
9
0
0
0
9
0
0
9
9
0
% G
% His:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% I
% Lys:
0
0
0
17
0
9
0
17
9
25
34
9
9
9
9
% K
% Leu:
9
0
17
9
0
17
9
0
0
17
17
34
17
0
9
% L
% Met:
0
0
9
0
0
9
0
0
0
9
0
9
0
0
0
% M
% Asn:
34
9
9
9
9
25
9
9
9
0
0
0
9
0
9
% N
% Pro:
17
9
34
9
42
0
0
0
17
9
9
9
9
0
9
% P
% Gln:
9
34
0
0
0
0
42
0
0
0
17
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% R
% Ser:
9
17
9
0
9
25
9
25
25
17
0
0
0
17
34
% S
% Thr:
0
0
0
0
0
9
9
0
9
9
0
9
34
9
0
% T
% Val:
0
0
0
25
9
0
0
9
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _