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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
9.09
Human Site:
S418
Identified Species:
18.18
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
S418
G
A
F
N
N
W
V
S
Q
E
E
S
E
L
C
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
S417
G
A
F
N
N
W
V
S
Q
E
E
S
E
L
C
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
Q409
G
E
P
D
P
K
P
Q
T
G
S
G
F
L
P
Dog
Lupus familis
XP_545600
481
53856
S417
G
A
F
N
S
W
A
S
Q
G
G
L
E
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
G368
Q
E
P
S
V
G
P
G
S
L
T
S
S
S
Q
Rat
Rattus norvegicus
Q6RUG5
435
48626
Q371
G
P
L
T
S
S
S
Q
F
L
P
S
R
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
V417
G
G
F
K
S
V
V
V
V
V
K
R
L
L
C
Chicken
Gallus gallus
XP_418682
516
58625
A450
H
G
W
A
A
N
S
A
S
P
L
S
I
P
Q
Frog
Xenopus laevis
NP_001080094
512
57900
S446
V
Q
G
W
T
A
N
S
G
T
S
S
C
Q
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
F475
E
A
I
S
N
D
T
F
L
P
P
N
I
L
K
Nematode Worm
Caenorhab. elegans
P91124
430
48887
T367
F
P
I
G
P
L
A
T
L
F
D
T
S
S
F
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
D624
P
A
P
P
Q
Y
S
D
L
F
A
D
R
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
100
13.3
53.3
N.A.
6.6
20
N.A.
33.3
6.6
13.3
N.A.
N.A.
N.A.
20
0
6.6
P-Site Similarity:
100
100
20
66.6
N.A.
13.3
26.6
N.A.
46.6
20
13.3
N.A.
N.A.
N.A.
33.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
9
9
9
17
9
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
25
% C
% Asp:
0
0
0
9
0
9
0
9
0
0
9
9
0
0
0
% D
% Glu:
9
17
0
0
0
0
0
0
0
17
17
0
25
0
0
% E
% Phe:
9
0
34
0
0
0
0
9
9
17
0
0
9
0
17
% F
% Gly:
50
17
9
9
0
9
0
9
9
17
9
9
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
0
0
0
0
0
0
17
0
0
% I
% Lys:
0
0
0
9
0
9
0
0
0
0
9
0
0
0
9
% K
% Leu:
0
0
9
0
0
9
0
0
25
17
9
9
9
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
25
25
9
9
0
0
0
0
9
0
0
0
% N
% Pro:
9
17
25
9
17
0
17
0
0
17
17
0
0
9
17
% P
% Gln:
9
9
0
0
9
0
0
17
25
0
0
0
0
9
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
17
0
0
% R
% Ser:
0
0
0
17
25
9
25
34
17
0
17
50
17
17
9
% S
% Thr:
0
0
0
9
9
0
9
9
9
9
9
9
0
0
0
% T
% Val:
9
0
0
0
9
9
25
9
9
9
0
0
0
9
0
% V
% Trp:
0
0
9
9
0
25
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _