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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
3.03
Human Site:
S374
Identified Species:
6.06
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
S374
E
C
Q
T
A
F
G
S
P
S
A
S
L
T
S
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
P374
C
Q
T
A
F
G
S
P
S
A
S
L
T
S
Q
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
F368
L
L
L
L
S
E
I
F
N
A
S
S
L
E
E
Dog
Lupus familis
XP_545600
481
53856
P374
C
Q
T
A
F
G
S
P
G
T
S
F
M
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
S327
D
D
F
E
K
E
F
S
F
L
N
S
L
L
S
Rat
Rattus norvegicus
Q6RUG5
435
48626
L330
E
F
S
F
L
S
S
L
L
S
P
T
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
P374
C
Q
T
A
F
G
Q
P
G
S
S
F
P
T
Q
Chicken
Gallus gallus
XP_418682
516
58625
S383
N
E
I
L
N
A
S
S
L
E
E
G
E
F
S
Frog
Xenopus laevis
NP_001080094
512
57900
E383
I
L
S
A
S
S
L
E
G
D
D
L
G
N
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
S391
L
I
L
D
N
N
V
S
H
T
D
I
I
Q
E
Nematode Worm
Caenorhab. elegans
P91124
430
48887
E326
G
E
E
E
V
Q
D
E
S
R
S
Q
C
D
S
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
N489
P
S
R
Q
G
A
N
N
L
L
G
E
E
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
0
13.3
0
N.A.
26.6
13.3
N.A.
13.3
13.3
0
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
100
20
33.3
26.6
N.A.
33.3
26.6
N.A.
20
13.3
6.6
N.A.
N.A.
N.A.
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
9
17
0
0
0
17
9
0
0
0
0
% A
% Cys:
25
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
9
0
9
0
0
9
0
0
9
17
0
0
9
9
% D
% Glu:
17
17
9
17
0
17
0
17
0
9
9
9
17
9
25
% E
% Phe:
0
9
9
9
25
9
9
9
9
0
0
17
0
9
0
% F
% Gly:
9
0
0
0
9
25
9
0
25
0
9
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
9
9
0
0
0
9
0
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
17
17
17
9
0
9
9
25
17
0
17
25
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% M
% Asn:
9
0
0
0
17
9
9
9
9
0
9
0
0
9
0
% N
% Pro:
9
0
0
0
0
0
0
25
9
0
9
0
9
0
0
% P
% Gln:
0
25
9
9
0
9
9
0
0
0
0
9
0
9
25
% Q
% Arg:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
0
9
17
0
17
17
34
34
17
25
42
25
9
25
34
% S
% Thr:
0
0
25
9
0
0
0
0
0
17
0
9
9
17
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _