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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ICA1L
All Species:
0
Human Site:
S348
Identified Species:
0
UniProt:
Q8NDH6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH6
NP_612477.3
482
54407
S348
E
D
F
E
K
E
F
S
F
L
N
N
L
L
S
Chimpanzee
Pan troglodytes
XP_001172921
481
54158
F348
D
F
E
K
E
F
S
F
L
N
N
L
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001085831
472
53342
A342
D
M
K
P
E
E
G
A
C
L
G
P
V
A
G
Dog
Lupus familis
XP_545600
481
53856
F348
D
F
E
K
E
F
S
F
L
N
N
L
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TY65
431
48141
R301
S
E
E
E
E
E
E
R
F
E
R
E
P
A
V
Rat
Rattus norvegicus
Q6RUG5
435
48626
P304
E
E
R
F
E
R
E
P
A
V
A
R
A
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508894
481
54258
K348
L
E
G
K
D
F
E
K
E
F
S
F
L
S
P
Chicken
Gallus gallus
XP_418682
516
58625
Q357
E
E
N
A
S
K
D
Q
F
A
K
S
L
E
S
Frog
Xenopus laevis
NP_001080094
512
57900
K357
F
Y
E
E
R
V
P
K
D
P
L
G
P
E
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392866
545
62009
M365
S
S
S
N
N
R
I
M
Q
S
I
S
E
I
E
Nematode Worm
Caenorhab. elegans
P91124
430
48887
R300
S
A
K
T
S
Q
P
R
G
N
E
E
E
L
K
Sea Urchin
Strong. purpuratus
XP_001198366
691
77094
E463
I
S
L
G
E
D
P
E
R
H
I
D
Q
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
48.1
87.5
N.A.
73.6
72.4
N.A.
70.7
49.2
48.8
N.A.
N.A.
N.A.
35.7
32.5
34.4
Protein Similarity:
100
96.6
62.6
92.1
N.A.
79.4
79.2
N.A.
79.2
64.5
66.4
N.A.
N.A.
N.A.
53.5
48.7
48.6
P-Site Identity:
100
20
13.3
13.3
N.A.
20
13.3
N.A.
6.6
26.6
6.6
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
100
40
40
33.3
N.A.
33.3
33.3
N.A.
26.6
46.6
20
N.A.
N.A.
N.A.
13.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
9
9
9
9
0
9
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
25
9
0
0
9
9
9
0
9
0
0
9
0
0
0
% D
% Glu:
25
34
34
25
50
25
25
9
9
9
9
17
17
17
9
% E
% Phe:
9
17
9
9
0
25
9
17
25
9
0
9
0
0
0
% F
% Gly:
0
0
9
9
0
0
9
0
9
0
9
9
0
9
17
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
17
0
0
9
0
% I
% Lys:
0
0
17
25
9
9
0
17
0
0
9
0
0
0
9
% K
% Leu:
9
0
9
0
0
0
0
0
17
17
9
17
42
25
0
% L
% Met:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
9
0
0
0
0
25
25
9
0
0
0
% N
% Pro:
0
0
0
9
0
0
25
9
0
9
0
9
17
0
25
% P
% Gln:
0
0
0
0
0
9
0
9
9
0
0
0
9
0
0
% Q
% Arg:
0
0
9
0
9
17
0
17
9
0
9
9
0
0
0
% R
% Ser:
25
17
9
0
17
0
17
9
0
9
9
17
0
25
25
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _