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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPEPL1
All Species:
26.36
Human Site:
S88
Identified Species:
44.62
UniProt:
Q8NDH3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDH3
NP_078939.3
523
55861
S88
C
R
V
S
R
H
N
S
P
S
A
A
H
F
I
Chimpanzee
Pan troglodytes
XP_525369
359
37700
Rhesus Macaque
Macaca mulatta
XP_001086311
463
49382
C82
L
P
P
G
A
H
R
C
I
V
M
V
C
E
Q
Dog
Lupus familis
XP_543071
397
42215
R20
G
D
A
D
P
Q
S
R
P
L
L
L
L
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6NSR8
524
55922
S88
S
R
V
S
R
H
N
S
P
S
A
A
H
F
I
Rat
Rattus norvegicus
NP_001101276
412
43664
R35
A
S
R
R
T
E
K
R
T
V
M
V
E
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511141
548
58651
S113
S
R
V
S
R
H
N
S
P
S
A
A
Q
F
I
Chicken
Gallus gallus
XP_417486
523
56072
S88
S
R
V
S
R
H
N
S
P
S
A
A
Q
F
I
Frog
Xenopus laevis
NP_001090314
521
55831
S88
S
R
V
S
R
H
N
S
P
S
A
A
H
F
I
Zebra Danio
Brachydanio rerio
NP_001017688
525
55746
S88
S
R
V
S
R
H
N
S
P
S
S
A
H
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650240
558
60151
T112
L
K
A
S
R
H
N
T
A
S
R
A
H
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34629
491
52431
T86
D
A
S
S
R
G
N
T
P
T
N
A
H
S
I
Sea Urchin
Strong. purpuratus
XP_780549
523
55941
A91
M
K
A
S
R
H
N
A
P
S
R
C
H
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151608
535
57316
A88
K
R
C
A
R
H
N
A
P
S
H
A
N
F
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.3
84.6
72
N.A.
94.6
74.3
N.A.
83.9
87.7
83.5
81.1
N.A.
58.4
N.A.
42.6
58.7
Protein Similarity:
100
67.8
85.8
74.1
N.A.
97.3
77
N.A.
89.2
94.4
92.1
90
N.A.
72.2
N.A.
56.5
74.9
P-Site Identity:
100
0
6.6
6.6
N.A.
93.3
6.6
N.A.
86.6
86.6
93.3
80
N.A.
53.3
N.A.
46.6
46.6
P-Site Similarity:
100
0
6.6
13.3
N.A.
93.3
6.6
N.A.
86.6
86.6
93.3
93.3
N.A.
66.6
N.A.
60
66.6
Percent
Protein Identity:
N.A.
58.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
74.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
80
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
22
8
8
0
0
15
8
0
36
65
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
8
0
0
0
8
8
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
8
% F
% Gly:
8
0
0
8
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
72
0
0
0
0
8
0
50
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
58
% I
% Lys:
8
15
0
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
15
0
0
0
0
0
0
0
0
8
8
8
8
0
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
72
0
0
0
8
0
8
0
0
% N
% Pro:
0
8
8
0
8
0
0
0
72
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
15
0
15
% Q
% Arg:
0
50
8
8
72
0
8
15
0
0
15
0
0
0
0
% R
% Ser:
36
8
8
65
0
0
8
43
0
65
8
0
0
8
0
% S
% Thr:
0
0
0
0
8
0
0
15
8
8
0
0
0
0
0
% T
% Val:
0
0
43
0
0
0
0
0
0
15
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _