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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR7A
All Species:
3.33
Human Site:
T475
Identified Species:
9.17
UniProt:
Q8NDA8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDA8
NP_001092750.1
1641
181249
T475
R
T
L
Y
L
V
S
T
T
V
D
R
M
S
H
Chimpanzee
Pan troglodytes
XP_526941
1585
180777
E465
V
V
P
A
E
Y
T
E
A
L
E
P
L
F
S
Rhesus Macaque
Macaca mulatta
XP_001085887
1562
178019
E465
V
V
P
A
E
Y
T
E
A
L
E
P
L
F
S
Dog
Lupus familis
XP_539211
1476
162783
I435
G
E
A
M
V
E
Y
I
V
Q
Q
C
A
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
A2RUW0
1122
123840
A81
N
D
I
S
N
P
N
A
S
G
A
A
T
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519112
1231
138043
H190
G
F
C
Y
A
L
Q
H
F
G
E
S
I
L
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919596
1544
173325
T478
N
T
L
H
L
F
T
T
T
V
G
R
L
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491711
1768
196725
N512
Q
A
L
Y
T
I
A
N
T
C
V
C
A
T
K
Sea Urchin
Strong. purpuratus
XP_001202192
933
104712
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.1
28.8
71.5
N.A.
N.A.
20.4
N.A.
49.4
N.A.
N.A.
43.8
N.A.
N.A.
N.A.
26.1
26.6
Protein Similarity:
100
49.2
48.8
80.2
N.A.
N.A.
36
N.A.
61.6
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
45.5
39.5
P-Site Identity:
100
0
0
0
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
26.6
26.6
6.6
N.A.
N.A.
20
N.A.
26.6
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
23
12
0
12
12
23
0
12
12
23
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
12
0
23
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
12
% D
% Glu:
0
12
0
0
23
12
0
23
0
0
34
0
0
0
12
% E
% Phe:
0
12
0
0
0
12
0
0
12
0
0
0
0
23
0
% F
% Gly:
23
0
0
0
0
0
0
0
0
23
12
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
12
% H
% Ile:
0
0
12
0
0
12
0
12
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
0
34
0
23
12
0
0
0
23
0
0
34
23
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
23
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% N
% Pro:
0
0
23
0
0
12
0
0
0
0
0
23
0
12
12
% P
% Gln:
12
0
0
0
0
0
12
0
0
12
12
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% R
% Ser:
0
0
0
12
0
0
12
0
12
0
0
12
0
12
34
% S
% Thr:
0
23
0
0
12
0
34
23
34
0
0
0
12
23
0
% T
% Val:
23
23
0
0
12
12
0
0
12
23
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
34
0
23
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _