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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR7A
All Species:
1.52
Human Site:
S729
Identified Species:
4.17
UniProt:
Q8NDA8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDA8
NP_001092750.1
1641
181249
S729
L
N
I
F
K
D
R
S
E
N
E
V
E
K
V
Chimpanzee
Pan troglodytes
XP_526941
1585
180777
A709
M
V
I
Y
G
A
V
A
L
H
A
P
K
K
Q
Rhesus Macaque
Macaca mulatta
XP_001085887
1562
178019
C713
V
L
L
L
H
G
Q
C
S
Q
V
L
G
M
S
Dog
Lupus familis
XP_539211
1476
162783
R677
Q
E
L
L
E
T
A
R
H
Q
E
E
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
A2RUW0
1122
123840
T323
M
D
S
S
F
V
V
T
D
T
S
T
L
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519112
1231
138043
E432
P
G
G
T
A
M
M
E
Y
I
V
R
Q
C
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919596
1544
173325
G727
R
K
A
S
G
I
F
G
L
L
K
V
G
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491711
1768
196725
M781
F
G
F
I
K
D
T
M
P
I
R
Q
Y
P
D
Sea Urchin
Strong. purpuratus
XP_001202192
933
104712
V134
G
N
K
L
C
N
D
V
M
E
D
L
Y
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.1
28.8
71.5
N.A.
N.A.
20.4
N.A.
49.4
N.A.
N.A.
43.8
N.A.
N.A.
N.A.
26.1
26.6
Protein Similarity:
100
49.2
48.8
80.2
N.A.
N.A.
36
N.A.
61.6
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
45.5
39.5
P-Site Identity:
100
13.3
0
6.6
N.A.
N.A.
0
N.A.
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
100
46.6
26.6
26.6
N.A.
N.A.
33.3
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
12
12
12
0
0
12
0
12
0
12
% A
% Cys:
0
0
0
0
12
0
0
12
0
0
0
0
0
12
0
% C
% Asp:
0
12
0
0
0
23
12
0
12
0
12
0
0
0
23
% D
% Glu:
0
12
0
0
12
0
0
12
12
12
23
12
12
12
0
% E
% Phe:
12
0
12
12
12
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
23
12
0
23
12
0
12
0
0
0
0
23
0
0
% G
% His:
0
0
0
0
12
0
0
0
12
12
0
0
0
0
0
% H
% Ile:
0
0
23
12
0
12
0
0
0
23
0
0
0
0
0
% I
% Lys:
0
12
12
0
23
0
0
0
0
0
12
0
12
34
12
% K
% Leu:
12
12
23
34
0
0
0
0
23
12
0
23
12
0
12
% L
% Met:
23
0
0
0
0
12
12
12
12
0
0
0
0
12
0
% M
% Asn:
0
23
0
0
0
12
0
0
0
12
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
0
0
0
12
0
0
12
0
12
0
% P
% Gln:
12
0
0
0
0
0
12
0
0
23
0
12
12
0
12
% Q
% Arg:
12
0
0
0
0
0
12
12
0
0
12
12
0
12
12
% R
% Ser:
0
0
12
23
0
0
0
12
12
0
12
0
0
0
12
% S
% Thr:
0
0
0
12
0
12
12
12
0
12
0
12
0
12
0
% T
% Val:
12
12
0
0
0
12
23
12
0
0
23
23
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
12
0
0
0
23
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _