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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR7A
All Species:
3.33
Human Site:
S1421
Identified Species:
9.17
UniProt:
Q8NDA8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDA8
NP_001092750.1
1641
181249
S1421
D
D
G
D
N
P
H
S
P
V
A
L
E
A
M
Chimpanzee
Pan troglodytes
XP_526941
1585
180777
V1361
Y
H
L
A
R
T
E
V
V
C
E
S
L
K
A
Rhesus Macaque
Macaca mulatta
XP_001085887
1562
178019
T1383
E
Q
D
D
V
R
L
T
A
I
F
L
F
E
D
Dog
Lupus familis
XP_539211
1476
162783
Q1318
M
K
A
L
V
C
T
Q
S
S
V
Y
E
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
A2RUW0
1122
123840
E964
Y
S
L
G
R
M
V
E
G
L
S
H
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519112
1231
138043
A1073
A
D
K
N
C
S
R
A
A
T
V
M
I
N
C
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919596
1544
173325
S1377
N
D
E
I
R
C
A
S
I
M
L
L
G
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491711
1768
196725
D1547
D
D
H
G
D
R
K
D
T
V
A
I
E
S
I
Sea Urchin
Strong. purpuratus
XP_001202192
933
104712
I775
A
S
R
V
E
T
N
I
L
K
N
I
N
P
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.1
28.8
71.5
N.A.
N.A.
20.4
N.A.
49.4
N.A.
N.A.
43.8
N.A.
N.A.
N.A.
26.1
26.6
Protein Similarity:
100
49.2
48.8
80.2
N.A.
N.A.
36
N.A.
61.6
N.A.
N.A.
64.7
N.A.
N.A.
N.A.
45.5
39.5
P-Site Identity:
100
0
13.3
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
33.3
0
P-Site Similarity:
100
0
33.3
6.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
40
N.A.
N.A.
N.A.
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
12
12
0
0
12
12
23
0
23
0
0
12
12
% A
% Cys:
0
0
0
0
12
23
0
0
0
12
0
0
0
0
12
% C
% Asp:
23
45
12
23
12
0
0
12
0
0
0
0
0
12
12
% D
% Glu:
12
0
12
0
12
0
12
12
0
0
12
0
34
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
12
0
0
% F
% Gly:
0
0
12
23
0
0
0
0
12
0
0
0
12
0
0
% G
% His:
0
12
12
0
0
0
12
0
0
0
0
12
0
0
12
% H
% Ile:
0
0
0
12
0
0
0
12
12
12
0
23
12
12
12
% I
% Lys:
0
12
12
0
0
0
12
0
0
12
0
0
0
12
0
% K
% Leu:
0
0
23
12
0
0
12
0
12
12
12
34
12
0
12
% L
% Met:
12
0
0
0
0
12
0
0
0
12
0
12
0
0
12
% M
% Asn:
12
0
0
12
12
0
12
0
0
0
12
0
12
23
0
% N
% Pro:
0
0
0
0
0
12
0
0
12
0
0
0
0
12
12
% P
% Gln:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
12
% Q
% Arg:
0
0
12
0
34
23
12
0
0
0
0
0
12
0
0
% R
% Ser:
0
23
0
0
0
12
0
23
12
12
12
12
0
12
0
% S
% Thr:
0
0
0
0
0
23
12
12
12
12
0
0
0
0
0
% T
% Val:
0
0
0
12
23
0
12
12
12
23
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _