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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSEN2
All Species:
13.94
Human Site:
S268
Identified Species:
23.59
UniProt:
Q8NCE0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NCE0
NP_001138864.1
465
53247
S268
E
E
A
E
C
A
M
S
E
R
E
A
A
P
N
Chimpanzee
Pan troglodytes
XP_001154212
465
53150
S268
E
E
A
E
C
A
M
S
E
R
E
A
A
P
N
Rhesus Macaque
Macaca mulatta
XP_001086495
465
53136
S268
E
E
V
E
C
A
M
S
E
R
E
D
A
P
N
Dog
Lupus familis
XP_541765
470
53597
S273
E
E
D
V
Y
D
V
S
E
Q
E
C
A
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6P7W5
460
52196
Q261
E
E
E
L
C
G
A
Q
E
E
E
A
A
A
A
Rat
Rattus norvegicus
Q5M954
463
52933
Q267
E
E
E
L
C
D
V
Q
E
G
A
A
P
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514951
417
47631
V226
C
E
E
E
Y
V
L
V
E
E
T
L
G
N
R
Chicken
Gallus gallus
Q5ZIN2
461
52116
P263
E
E
E
S
S
L
C
P
E
E
G
S
A
R
E
Frog
Xenopus laevis
NP_001085705
460
52851
D261
E
E
V
Q
E
N
V
D
L
G
P
E
G
T
E
Zebra Danio
Brachydanio rerio
NP_001070119
438
50386
T245
D
E
R
S
Q
H
I
T
Q
E
N
S
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784204
689
77890
E368
D
Q
T
S
I
E
G
E
K
K
R
S
S
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M1E8
237
27341
E49
C
N
V
L
L
S
V
E
S
E
E
A
E
L
L
Baker's Yeast
Sacchar. cerevisiae
P16658
377
44091
Q189
E
D
V
G
I
V
A
Q
Q
Q
D
I
S
E
S
Red Bread Mold
Neurospora crassa
Q9P6Y2
633
70085
I438
L
N
V
E
P
T
V
I
S
Q
E
L
V
D
K
Conservation
Percent
Protein Identity:
100
99.1
92.6
77.6
N.A.
68.1
70.1
N.A.
58.2
54.6
52.4
43.4
N.A.
N.A.
N.A.
N.A.
26.1
Protein Similarity:
100
99.5
95.4
85.1
N.A.
78.7
80.2
N.A.
70.9
71.8
66.4
59.7
N.A.
N.A.
N.A.
N.A.
40.4
P-Site Identity:
100
100
86.6
53.3
N.A.
46.6
33.3
N.A.
20
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
66.6
N.A.
46.6
46.6
N.A.
26.6
33.3
26.6
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.9
21.1
Protein Similarity:
N.A.
N.A.
N.A.
32.6
39.3
37.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
22
15
0
0
0
8
36
43
8
8
% A
% Cys:
15
0
0
0
36
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
15
8
8
0
0
15
0
8
0
0
8
8
0
8
15
% D
% Glu:
65
72
29
36
8
8
0
15
58
36
50
8
8
8
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
8
0
0
15
8
0
15
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
0
15
0
8
8
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% K
% Leu:
8
0
0
22
8
8
8
0
8
0
0
15
0
8
8
% L
% Met:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
8
0
0
0
0
8
0
0
8
29
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
8
0
8
29
0
% P
% Gln:
0
8
0
8
8
0
0
22
15
22
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
22
8
0
0
8
8
% R
% Ser:
0
0
0
22
8
8
0
29
15
0
0
22
22
0
8
% S
% Thr:
0
0
8
0
0
8
0
8
0
0
8
0
0
15
0
% T
% Val:
0
0
36
8
0
15
36
8
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _