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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
19.7
Human Site:
Y391
Identified Species:
27.08
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
Y391
E
R
N
I
C
S
K
Y
S
V
R
G
Y
P
T
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
Y350
E
R
N
I
C
S
K
Y
S
V
R
G
Y
P
T
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
Y348
E
R
S
I
C
S
K
Y
S
V
R
G
Y
P
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
Y376
E
R
N
V
C
S
K
Y
S
V
R
G
Y
P
T
Rat
Rattus norvegicus
P38659
643
72702
Y593
N
D
I
T
N
D
R
Y
K
V
E
G
F
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
S324
H
A
I
C
S
K
F
S
V
R
G
Y
P
T
L
Chicken
Gallus gallus
Q8JG64
505
56163
Y443
A
N
D
V
P
S
P
Y
E
V
R
G
F
P
T
Frog
Xenopus laevis
Q6NRT6
796
90966
A739
Y
E
H
L
C
N
S
A
S
I
R
S
Y
P
T
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
S287
R
T
L
C
N
R
F
S
V
R
G
Y
P
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
Q374
N
K
Q
V
C
I
D
Q
Q
V
E
G
Y
P
T
Honey Bee
Apis mellifera
XP_392102
374
42835
Q331
S
K
E
L
C
N
E
Q
E
V
D
G
F
P
T
Nematode Worm
Caenorhab. elegans
P34329
618
69779
F569
I
N
D
A
P
S
Q
F
A
V
E
G
F
P
T
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
H356
E
K
P
L
C
K
K
H
A
I
E
G
Y
P
T
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
M318
S
K
A
A
K
N
C
M
A
K
G
D
Y
A
K
Maize
Zea mays
NP_001105759
366
40038
K326
A
A
K
K
I
I
D
K
G
S
D
Y
T
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
S321
K
S
Y
I
E
K
G
S
D
Y
A
S
K
E
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
R329
Y
A
T
K
E
F
A
R
L
E
G
I
L
K
K
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
33.3
N.A.
0
46.6
40
0
N.A.
40
33.3
33.3
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
46.6
N.A.
0
66.6
66.6
0
N.A.
53.3
66.6
66.6
80
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
6.6
0
N.A.
13.3
N.A.
0
P-Site Similarity:
26.6
0
N.A.
20
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
18
6
12
0
0
6
6
18
0
6
0
0
6
0
% A
% Cys:
0
0
0
12
48
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
12
0
0
6
12
0
6
0
12
6
0
0
0
% D
% Glu:
30
6
6
0
12
0
6
0
12
6
24
0
0
6
0
% E
% Phe:
0
0
0
0
0
6
12
6
0
0
0
0
24
0
0
% F
% Gly:
0
0
0
0
0
0
6
0
6
0
24
59
0
0
0
% G
% His:
6
0
6
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
6
0
12
24
6
12
0
0
0
12
0
6
0
0
0
% I
% Lys:
6
24
6
12
6
18
30
6
6
6
0
0
6
12
18
% K
% Leu:
0
0
6
18
0
0
0
0
6
0
0
0
6
0
12
% L
% Met:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
12
12
18
0
12
18
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
12
0
6
0
0
0
0
0
12
65
0
% P
% Gln:
0
0
6
0
0
0
6
12
6
0
0
0
0
0
0
% Q
% Arg:
6
24
0
0
0
6
6
6
0
12
36
0
0
0
0
% R
% Ser:
12
6
6
0
6
36
6
18
30
6
0
12
0
0
0
% S
% Thr:
0
6
6
6
0
0
0
0
0
0
0
0
6
12
71
% T
% Val:
0
0
0
18
0
0
0
0
12
53
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
6
0
0
0
0
36
0
6
0
18
48
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _