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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
20.3
Human Site:
Y289
Identified Species:
27.92
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
Y289
D
L
E
S
L
R
E
Y
V
E
S
Q
L
Q
R
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
Y248
D
L
E
S
L
R
E
Y
V
E
S
Q
L
Q
R
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
Y246
D
L
E
S
L
R
E
Y
V
E
L
Q
L
Q
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
Y275
D
L
E
S
L
R
D
Y
V
Q
S
Q
L
Q
G
Rat
Rattus norvegicus
P38659
643
72702
D492
A
M
E
P
E
E
F
D
S
D
A
L
Q
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
S225
S
L
K
E
Y
I
D
S
Q
L
Q
N
A
D
D
Chicken
Gallus gallus
Q8JG64
505
56163
D343
M
Q
E
E
F
S
R
D
G
K
A
L
E
R
F
Frog
Xenopus laevis
Q6NRT6
796
90966
C420
E
L
Y
I
H
K
P
C
V
A
A
F
K
G
K
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
K188
E
F
V
D
N
H
V
K
A
A
E
S
K
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
Y266
D
L
S
T
L
K
T
Y
V
E
K
M
V
G
V
Honey Bee
Apis mellifera
XP_392102
374
42835
H231
K
Y
T
G
Q
R
T
H
E
E
L
K
A
Y
V
Nematode Worm
Caenorhab. elegans
P34329
618
69779
L468
P
D
E
F
D
G
E
L
D
E
N
L
E
A
F
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
Y247
D
H
V
A
M
K
E
Y
V
S
K
M
T
K
G
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
T219
Y
G
V
S
G
F
P
T
L
K
F
F
P
K
G
Maize
Zea mays
NP_001105759
366
40038
K227
V
S
G
F
P
T
L
K
F
F
P
K
G
N
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
F222
G
F
P
T
L
K
F
F
P
K
D
N
K
A
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
P230
F
P
K
G
S
T
T
P
E
D
Y
N
G
G
R
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
93.3
N.A.
N.A.
80
6.6
N.A.
6.6
6.6
13.3
0
N.A.
40
13.3
20
26.6
P-Site Similarity:
100
100
93.3
N.A.
N.A.
93.3
33.3
N.A.
20
26.6
40
6.6
N.A.
60
26.6
26.6
53.3
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
6.6
0
N.A.
6.6
N.A.
6.6
P-Site Similarity:
26.6
13.3
N.A.
33.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
6
0
0
0
0
6
12
18
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
36
6
0
6
6
0
12
12
6
12
6
0
0
12
6
% D
% Glu:
12
0
42
12
6
6
30
0
12
36
6
0
12
6
6
% E
% Phe:
6
12
0
12
6
6
12
6
6
6
6
12
0
0
18
% F
% Gly:
6
6
6
12
6
6
0
0
6
0
0
0
12
18
24
% G
% His:
0
6
0
0
6
6
0
6
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% I
% Lys:
6
0
12
0
0
24
0
12
0
18
12
12
18
12
12
% K
% Leu:
0
42
0
0
36
0
6
6
6
6
12
18
24
0
0
% L
% Met:
6
6
0
0
6
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
6
0
0
0
0
0
6
18
0
6
0
% N
% Pro:
6
6
6
6
6
0
12
6
6
0
6
0
6
0
0
% P
% Gln:
0
6
0
0
6
0
0
0
6
6
6
24
6
24
0
% Q
% Arg:
0
0
0
0
0
30
6
0
0
0
0
0
0
6
24
% R
% Ser:
6
6
6
30
6
6
0
6
6
6
18
6
0
0
0
% S
% Thr:
0
0
6
12
0
12
18
6
0
0
0
0
6
0
0
% T
% Val:
6
0
18
0
0
0
6
0
42
0
0
0
6
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
6
6
0
6
0
0
36
0
0
6
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _