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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
13.03
Human Site:
Y251
Identified Species:
17.92
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
Y251
K
V
D
C
T
Q
H
Y
E
L
C
S
G
N
Q
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
Y210
K
V
D
C
T
Q
H
Y
E
L
C
S
G
N
Q
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
Y208
K
V
D
C
T
Q
H
Y
E
L
C
S
G
N
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
Y237
K
V
D
C
T
Q
H
Y
A
V
C
S
E
H
Q
Rat
Rattus norvegicus
P38659
643
72702
E454
T
F
A
I
A
D
E
E
D
Y
A
T
E
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
C187
C
T
E
H
Y
E
L
C
S
G
N
Q
V
R
G
Chicken
Gallus gallus
Q8JG64
505
56163
F305
A
V
A
S
R
K
T
F
G
H
E
L
S
E
F
Frog
Xenopus laevis
Q6NRT6
796
90966
L382
G
T
D
E
Q
S
S
L
P
E
F
K
K
L
T
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
N150
H
Y
E
V
C
S
D
N
Q
V
R
G
Y
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
R228
K
I
D
C
T
Q
F
R
S
I
C
Q
D
F
E
Honey Bee
Apis mellifera
XP_392102
374
42835
V193
N
Y
V
S
I
S
K
V
D
C
T
Q
H
R
S
Nematode Worm
Caenorhab. elegans
P34329
618
69779
A430
V
A
D
E
E
E
F
A
K
E
L
E
E
L
G
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
R209
K
V
D
C
T
A
H
R
A
V
C
D
Q
Y
G
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
T181
H
C
K
N
L
A
P
T
Y
E
K
V
A
T
A
Maize
Zea mays
NP_001105759
366
40038
E189
K
H
L
A
P
I
Y
E
K
L
A
S
V
F
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
V184
L
A
P
T
Y
E
K
V
A
T
V
F
K
Q
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
E192
A
T
F
A
S
D
P
E
I
T
I
A
K
V
D
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
0
N.A.
0
6.6
6.6
0
N.A.
40
0
6.6
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
20
N.A.
13.3
20
6.6
20
N.A.
60
6.6
20
53.3
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
0
20
N.A.
0
N.A.
0
P-Site Similarity:
0
40
N.A.
13.3
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
12
6
12
0
6
18
0
12
6
6
0
6
% A
% Cys:
6
6
0
36
6
0
0
6
0
6
36
0
0
0
0
% C
% Asp:
0
0
48
0
0
12
6
0
12
0
0
6
6
0
6
% D
% Glu:
0
0
12
12
6
18
6
18
18
18
6
6
18
6
12
% E
% Phe:
0
6
6
0
0
0
12
6
0
0
6
6
0
12
6
% F
% Gly:
6
0
0
0
0
0
0
0
6
6
0
6
18
0
18
% G
% His:
12
6
0
6
0
0
30
0
0
6
0
0
6
6
0
% H
% Ile:
0
6
0
6
6
6
0
0
6
6
6
0
0
0
0
% I
% Lys:
42
0
6
0
0
6
12
0
12
0
6
6
18
0
12
% K
% Leu:
6
0
6
0
6
0
6
6
0
24
6
6
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
6
0
0
0
6
0
0
6
0
0
18
0
% N
% Pro:
0
0
6
0
6
0
12
0
6
0
0
0
0
6
0
% P
% Gln:
0
0
0
0
6
30
0
0
6
0
0
18
6
6
24
% Q
% Arg:
0
0
0
0
6
0
0
12
0
0
6
0
0
12
0
% R
% Ser:
0
0
0
12
6
18
6
0
12
0
0
30
6
0
6
% S
% Thr:
6
18
0
6
36
0
6
6
0
12
6
6
0
6
12
% T
% Val:
6
36
6
6
0
0
0
12
0
18
6
6
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
12
0
6
24
6
6
0
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _