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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
9.7
Human Site:
T299
Identified Species:
13.33
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
T299
S
Q
L
Q
R
T
E
T
G
A
T
E
T
V
T
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
T258
S
Q
L
Q
R
T
A
T
G
A
T
E
T
V
T
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
T256
L
Q
L
Q
R
T
E
T
G
A
T
E
T
V
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
A285
S
Q
L
Q
G
S
E
A
A
P
E
T
V
E
P
Rat
Rattus norvegicus
P38659
643
72702
A502
A
L
Q
E
F
V
M
A
F
K
K
G
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
E235
Q
N
A
D
D
A
P
E
A
P
K
P
S
E
I
Chicken
Gallus gallus
Q8JG64
505
56163
D353
A
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
Frog
Xenopus laevis
Q6NRT6
796
90966
S430
A
F
K
G
K
G
I
S
A
Y
E
I
H
H
G
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
K198
E
S
K
D
E
P
E
K
E
E
E
H
T
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
E276
K
M
V
G
V
P
L
E
K
T
A
G
E
A
G
Honey Bee
Apis mellifera
XP_392102
374
42835
M241
L
K
A
Y
V
S
K
M
L
E
K
E
N
D
Q
Nematode Worm
Caenorhab. elegans
P34329
618
69779
Q478
N
L
E
A
F
M
K
Q
I
S
S
G
K
A
K
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
A257
K
M
T
K
G
A
E
A
A
P
L
P
G
S
E
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
A229
F
F
P
K
G
N
K
A
G
E
D
Y
E
G
G
Maize
Zea mays
NP_001105759
366
40038
E237
P
K
G
N
K
A
G
E
D
Y
D
G
G
R
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
Y232
D
N
K
A
G
H
D
Y
D
G
G
R
D
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
A240
Y
N
G
G
R
S
E
A
D
L
V
K
F
L
N
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
93.3
86.6
N.A.
N.A.
33.3
0
N.A.
0
0
0
13.3
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
93.3
86.6
N.A.
N.A.
40
20
N.A.
6.6
26.6
20
13.3
N.A.
6.6
26.6
26.6
13.3
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
6.6
0
N.A.
0
N.A.
13.3
P-Site Similarity:
20
13.3
N.A.
13.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
12
12
0
18
6
30
24
18
6
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
12
6
0
6
6
18
0
18
0
6
6
12
% D
% Glu:
6
0
12
6
6
0
36
18
6
18
18
24
12
12
12
% E
% Phe:
6
12
0
0
18
0
0
0
6
6
0
0
6
0
0
% F
% Gly:
0
0
12
18
24
6
6
0
24
6
6
30
12
6
18
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
6
6
12
0
% H
% Ile:
0
0
0
0
0
0
6
0
6
0
0
6
0
0
6
% I
% Lys:
12
12
18
12
12
0
18
6
6
6
18
6
12
0
24
% K
% Leu:
12
18
24
0
0
6
6
0
6
6
6
0
0
24
0
% L
% Met:
0
12
0
0
0
6
6
6
0
0
0
0
0
0
0
% M
% Asn:
6
18
0
6
0
6
0
0
0
0
0
0
12
0
6
% N
% Pro:
6
0
6
0
0
12
6
0
0
18
0
12
0
0
6
% P
% Gln:
6
24
6
24
0
0
6
6
0
0
0
0
0
0
6
% Q
% Arg:
0
0
0
6
24
0
0
0
0
0
0
6
0
6
0
% R
% Ser:
18
6
0
0
0
18
0
6
0
6
6
0
6
6
0
% S
% Thr:
0
0
6
0
0
18
0
18
0
6
18
6
24
0
12
% T
% Val:
0
0
6
0
12
6
0
0
0
0
6
0
6
18
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
6
0
0
0
6
6
12
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _