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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
13.64
Human Site:
T174
Identified Species:
18.75
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
T174
T
L
N
E
E
P
V
T
P
E
P
E
V
E
P
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
T133
T
L
N
E
E
P
V
T
P
E
P
E
V
E
P
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
T131
T
L
S
E
E
P
A
T
P
E
P
E
V
E
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
T160
T
L
N
E
E
P
A
T
P
E
P
E
A
E
P
Rat
Rattus norvegicus
P38659
643
72702
I288
S
G
P
P
S
K
E
I
L
T
L
K
Q
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
L124
A
P
E
P
K
Q
G
L
Y
E
L
S
A
A
N
Chicken
Gallus gallus
Q8JG64
505
56163
A136
Q
A
G
P
A
S
V
A
L
S
S
V
A
D
F
Frog
Xenopus laevis
Q6NRT6
796
90966
E240
Y
I
S
S
T
V
T
E
L
W
A
G
N
F
R
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
L87
P
K
Q
G
L
Y
E
L
T
A
T
N
F
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
E149
K
E
L
S
A
P
A
E
A
D
L
G
E
V
K
Honey Bee
Apis mellifera
XP_392102
374
42835
I129
T
F
G
S
E
N
I
I
P
S
P
P
E
A
V
Nematode Worm
Caenorhab. elegans
P34329
618
69779
P144
R
V
D
P
N
Y
K
P
P
P
E
E
V
V
T
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
D138
E
L
N
P
Q
E
A
D
V
P
Q
V
P
A
A
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
R118
P
K
K
Y
E
G
P
R
T
A
E
A
L
T
E
Maize
Zea mays
NP_001105759
366
40038
V126
K
Y
E
G
Q
R
S
V
E
A
L
A
E
F
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
A121
E
G
P
R
N
A
E
A
L
A
E
Y
V
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
T129
S
N
F
I
A
E
K
T
G
V
K
A
R
K
K
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
86.6
N.A.
N.A.
86.6
0
N.A.
6.6
6.6
0
0
N.A.
6.6
26.6
20
13.3
P-Site Similarity:
100
100
93.3
N.A.
N.A.
86.6
13.3
N.A.
13.3
13.3
13.3
6.6
N.A.
13.3
33.3
33.3
20
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
6.6
0
N.A.
6.6
N.A.
6.6
P-Site Similarity:
13.3
6.6
N.A.
6.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
0
18
6
24
12
6
24
6
18
18
18
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
0
0
6
0
6
0
0
0
6
0
% D
% Glu:
12
6
12
24
36
12
18
12
6
30
18
30
18
24
6
% E
% Phe:
0
6
6
0
0
0
0
0
0
0
0
0
6
12
6
% F
% Gly:
0
12
12
12
0
6
6
0
6
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
0
0
6
12
0
0
0
0
0
0
0
% I
% Lys:
12
12
6
0
6
6
12
0
0
0
6
6
0
12
18
% K
% Leu:
0
30
6
0
6
0
0
12
24
0
24
0
6
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
24
0
12
6
0
0
0
0
0
6
6
6
6
% N
% Pro:
12
6
12
30
0
30
6
6
36
12
30
6
6
0
24
% P
% Gln:
6
0
6
0
12
6
0
0
0
0
6
0
6
0
6
% Q
% Arg:
6
0
0
6
0
6
0
6
0
0
0
0
6
0
6
% R
% Ser:
12
0
12
18
6
6
6
0
0
12
6
6
0
0
6
% S
% Thr:
30
0
0
0
6
0
6
30
12
6
6
0
0
6
6
% T
% Val:
0
6
0
0
0
6
18
6
6
6
0
12
30
18
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
6
6
0
6
0
12
0
0
6
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _