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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXNDC5 All Species: 14.24
Human Site: S419 Identified Species: 19.58
UniProt: Q8NBS9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBS9 NP_001139021.1 432 47629 S419 S G G R D L D S L H R F V L S
Chimpanzee Pan troglodytes XP_001165912 391 44022 S378 S G G R D L D S L H R F V L G
Rhesus Macaque Macaca mulatta XP_001085723 389 43644 S376 S G G R D L D S L H R F V L G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q91W90 417 46397 S404 N G G R D L D S L H S F V L R
Rat Rattus norvegicus P38659 643 72702 D621 K F E G G N R D L E H L S K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514270 364 40832 L352 G A R D L E T L H S F V L R Q
Chicken Gallus gallus Q8JG64 505 56163 V471 K Y E G G R E V S D F I S Y L
Frog Xenopus laevis Q6NRT6 796 90966 S767 Y F G E Q I D S R D A K E I A
Zebra Danio Brachydanio rerio NP_998181 327 37321 L315 G G R D L E S L H S F I M K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572742 416 46632 E402 E G S R S L P E L Q A Y L K K
Honey Bee Apis mellifera XP_392102 374 42835 D359 N G A R N L D D L Y E F I M I
Nematode Worm Caenorhab. elegans P34329 618 69779 L597 K Y S G N R D L E D L K K F M
Sea Urchin Strong. purpuratus XP_001201177 398 44341 A384 S G T R T L A A L E T Y L K S
Poplar Tree Populus trichocarpa XP_002320314 358 39382 E346 I S P A K A D E F T L K K N I
Maize Zea mays NP_001105759 366 40038 F354 S P S K A D E F I V K K N I L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O22263 361 39478 L349 V K A D E L T L K R N I L T T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q92249 369 39263 F357 K V N V L R K F V E K A A E E
Conservation
Percent
Protein Identity: 100 75.6 79.6 N.A. N.A. 84 23 N.A. 64.1 22.7 20.8 49.7 N.A. 41.9 41.6 24.6 44.2
Protein Similarity: 100 80.3 82.1 N.A. N.A. 88.8 35.2 N.A. 72.2 38.2 31 62.9 N.A. 57.4 57.1 38 59.2
P-Site Identity: 100 93.3 93.3 N.A. N.A. 80 6.6 N.A. 0 0 20 6.6 N.A. 26.6 40 6.6 40
P-Site Similarity: 100 93.3 93.3 N.A. N.A. 86.6 6.6 N.A. 6.6 6.6 40 13.3 N.A. 40 73.3 13.3 60
Percent
Protein Identity: 26.6 28.2 N.A. 26.3 N.A. 27.5
Protein Similarity: 41.9 41.6 N.A. 41.9 N.A. 41.2
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. 0
P-Site Similarity: 6.6 40 N.A. 26.6 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 12 6 6 6 6 6 0 0 12 6 6 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 18 24 6 48 12 0 18 0 0 0 0 0 % D
% Glu: 6 0 12 6 6 12 12 12 6 18 6 0 6 6 6 % E
% Phe: 0 12 0 0 0 0 0 12 6 0 18 30 0 6 6 % F
% Gly: 12 48 30 18 12 0 0 0 0 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 12 24 6 0 0 0 0 % H
% Ile: 6 0 0 0 0 6 0 0 6 0 0 18 6 12 12 % I
% Lys: 24 6 0 6 6 0 6 0 6 0 12 24 12 24 6 % K
% Leu: 0 0 0 0 18 48 0 24 48 0 12 6 24 24 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 6 6 6 % M
% Asn: 12 0 6 0 12 6 0 0 0 0 6 0 6 6 0 % N
% Pro: 0 6 6 0 0 0 6 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 6 0 0 0 0 6 0 0 0 0 12 % Q
% Arg: 0 0 12 42 0 18 6 0 6 6 18 0 0 6 6 % R
% Ser: 30 6 18 0 6 0 6 30 6 12 6 0 12 0 12 % S
% Thr: 0 0 6 0 6 0 12 0 0 6 6 0 0 6 6 % T
% Val: 6 6 0 6 0 0 0 6 6 6 0 6 24 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 12 0 0 0 0 0 0 0 6 0 12 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _