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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
14.55
Human Site:
S412
Identified Species:
20
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
S412
G
K
K
V
S
E
H
S
G
G
R
D
L
D
S
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
S371
G
K
K
V
S
E
H
S
G
G
R
D
L
D
S
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
S369
G
K
K
V
S
E
H
S
G
G
R
D
L
D
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
N397
G
E
K
V
G
E
H
N
G
G
R
D
L
D
S
Rat
Rattus norvegicus
P38659
643
72702
K614
G
D
K
K
N
P
I
K
F
E
G
G
N
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
G345
E
M
I
K
E
H
S
G
A
R
D
L
E
T
L
Chicken
Gallus gallus
Q8JG64
505
56163
K464
G
K
K
Q
S
P
K
K
Y
E
G
G
R
E
V
Frog
Xenopus laevis
Q6NRT6
796
90966
Y760
N
G
S
K
K
K
D
Y
F
G
E
Q
I
D
S
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
G308
Q
Q
G
E
E
H
N
G
G
R
D
L
E
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
E395
G
Q
R
Q
N
E
Y
E
G
S
R
S
L
P
E
Honey Bee
Apis mellifera
XP_392102
374
42835
N352
G
L
K
V
S
E
Y
N
G
A
R
N
L
D
D
Nematode Worm
Caenorhab. elegans
P34329
618
69779
K590
G
K
K
S
E
P
I
K
Y
S
G
N
R
D
L
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
S377
G
E
M
V
E
K
H
S
G
T
R
T
L
A
A
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
I339
Q
R
M
L
Q
K
T
I
S
P
A
K
A
D
E
Maize
Zea mays
NP_001105759
366
40038
S347
R
M
L
E
K
S
I
S
P
S
K
A
D
E
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
V342
L
G
K
S
I
S
P
V
K
A
D
E
L
T
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
K350
K
V
D
E
L
T
V
K
V
N
V
L
R
K
F
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
100
N.A.
N.A.
80
13.3
N.A.
0
26.6
20
6.6
N.A.
33.3
60
26.6
46.6
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
20
N.A.
0
33.3
33.3
20
N.A.
60
80
33.3
66.6
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
6.6
6.6
N.A.
13.3
N.A.
0
P-Site Similarity:
26.6
20
N.A.
20
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
12
6
6
6
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
6
0
0
0
6
0
0
0
18
24
6
48
12
% D
% Glu:
6
12
0
18
24
36
0
6
0
12
6
6
12
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% F
% Gly:
59
12
6
0
6
0
0
12
48
30
18
12
0
0
0
% G
% His:
0
0
0
0
0
12
30
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
6
0
18
6
0
0
0
0
6
0
0
% I
% Lys:
6
30
53
18
12
18
6
24
6
0
6
6
0
6
0
% K
% Leu:
6
6
6
6
6
0
0
0
0
0
0
18
48
0
24
% L
% Met:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
12
0
6
12
0
6
0
12
6
0
0
% N
% Pro:
0
0
0
0
0
18
6
0
6
6
0
0
0
6
0
% P
% Gln:
12
12
0
12
6
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
6
6
6
0
0
0
0
0
0
12
42
0
18
6
0
% R
% Ser:
0
0
6
12
30
12
6
30
6
18
0
6
0
6
30
% S
% Thr:
0
0
0
0
0
6
6
0
0
6
0
6
0
12
0
% T
% Val:
0
6
0
36
0
0
6
6
6
0
6
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
6
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _