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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC5
All Species:
14.55
Human Site:
S195
Identified Species:
20
UniProt:
Q8NBS9
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBS9
NP_001139021.1
432
47629
S195
K
Q
G
L
Y
E
L
S
A
S
N
F
E
L
H
Chimpanzee
Pan troglodytes
XP_001165912
391
44022
S154
K
Q
G
L
Y
E
L
S
A
S
N
F
E
L
H
Rhesus Macaque
Macaca mulatta
XP_001085723
389
43644
S152
K
Q
G
L
Y
E
L
S
A
S
N
F
E
L
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q91W90
417
46397
S181
K
Q
G
L
Y
E
L
S
A
N
N
F
E
L
H
Rat
Rattus norvegicus
P38659
643
72702
V309
D
D
V
V
I
L
G
V
F
Q
G
V
G
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514270
364
40832
F145
T
G
N
H
F
I
K
F
F
A
P
W
C
G
H
Chicken
Gallus gallus
Q8JG64
505
56163
F157
K
D
A
S
V
V
G
F
F
R
D
A
S
G
D
Frog
Xenopus laevis
Q6NRT6
796
90966
L261
F
S
S
G
V
G
W
L
I
T
F
C
S
D
T
Zebra Danio
Brachydanio rerio
NP_998181
327
37321
P108
H
F
V
K
F
F
A
P
W
C
G
H
C
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572742
416
46632
D170
L
N
I
G
K
V
V
D
L
T
E
D
T
F
A
Honey Bee
Apis mellifera
XP_392102
374
42835
H150
T
E
D
N
F
D
K
H
V
S
S
G
Y
H
F
Nematode Worm
Caenorhab. elegans
P34329
618
69779
E165
D
D
F
I
S
N
N
E
L
V
L
V
E
F
Y
Sea Urchin
Strong. purpuratus
XP_001201177
398
44341
D159
L
T
V
A
T
F
K
D
H
V
A
K
G
N
H
Poplar Tree
Populus trichocarpa
XP_002320314
358
39382
A139
G
T
N
V
K
I
A
A
V
P
S
N
V
A
V
Maize
Zea mays
NP_001105759
366
40038
P147
N
V
K
I
A
A
I
P
S
S
V
V
V
L
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22263
361
39478
N142
K
L
A
A
V
P
Q
N
V
V
V
L
T
P
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q92249
369
39263
T150
V
N
I
L
N
D
A
T
I
K
G
A
I
G
G
Conservation
Percent
Protein Identity:
100
75.6
79.6
N.A.
N.A.
84
23
N.A.
64.1
22.7
20.8
49.7
N.A.
41.9
41.6
24.6
44.2
Protein Similarity:
100
80.3
82.1
N.A.
N.A.
88.8
35.2
N.A.
72.2
38.2
31
62.9
N.A.
57.4
57.1
38
59.2
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
0
N.A.
6.6
6.6
0
0
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
26.6
13.3
6.6
6.6
N.A.
13.3
33.3
20
6.6
Percent
Protein Identity:
26.6
28.2
N.A.
26.3
N.A.
27.5
Protein Similarity:
41.9
41.6
N.A.
41.9
N.A.
41.2
P-Site Identity:
0
13.3
N.A.
6.6
N.A.
6.6
P-Site Similarity:
20
33.3
N.A.
13.3
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
6
6
18
6
24
6
6
12
0
6
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
6
12
0
0
% C
% Asp:
12
18
6
0
0
12
0
12
0
0
6
6
0
12
12
% D
% Glu:
0
6
0
0
0
24
0
6
0
0
6
0
30
0
0
% E
% Phe:
6
6
6
0
18
12
0
12
18
0
6
24
0
12
6
% F
% Gly:
6
6
24
12
0
6
12
0
0
0
18
6
12
18
6
% G
% His:
6
0
0
6
0
0
0
6
6
0
0
6
0
6
36
% H
% Ile:
0
0
12
12
6
12
6
0
12
0
0
0
6
0
0
% I
% Lys:
36
0
6
6
12
0
18
0
0
6
0
6
0
6
0
% K
% Leu:
12
6
0
30
0
6
24
6
12
0
6
6
0
30
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
12
12
6
6
6
6
6
0
6
24
6
0
6
0
% N
% Pro:
0
0
0
0
0
6
0
12
0
6
6
0
0
6
6
% P
% Gln:
0
24
0
0
0
0
6
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% R
% Ser:
0
6
6
6
6
0
0
24
6
30
12
0
12
0
0
% S
% Thr:
12
12
0
0
6
0
0
6
0
12
0
0
12
0
12
% T
% Val:
6
6
18
12
18
12
6
6
18
18
12
18
12
0
6
% V
% Trp:
0
0
0
0
0
0
6
0
6
0
0
6
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
0
0
0
0
0
6
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _