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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL23 All Species: 35.15
Human Site: Y433 Identified Species: 85.93
UniProt: Q8NBE8 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NBE8 NP_653312.2 558 63923 Y433 G Y R G S C T Y D K V Q S Y N
Chimpanzee Pan troglodytes XP_515889 558 63891 Y433 G Y R G S C T Y D K V Q S Y N
Rhesus Macaque Macaca mulatta XP_001104950 558 63891 Y433 G Y R G S C T Y D K V Q S Y N
Dog Lupus familis XP_545514 558 63871 Y433 G Y R G S C T Y D K V Q S Y N
Cat Felis silvestris
Mouse Mus musculus Q6GQU2 558 63821 Y433 G Y R G S C T Y D K V Q S Y N
Rat Rattus norvegicus Q56A24 600 68346 S469 G P D D N T C S D K V Q S Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514763 558 63599 Y433 G Y R G S C T Y D K V Q T Y N
Chicken Gallus gallus XP_426582 558 63291 Y433 G Y R G S C T Y D K I Q R Y H
Frog Xenopus laevis Q6INL2 589 66424 T447 A M K Y N A L T L Q C Y N P A
Zebra Danio Brachydanio rerio XP_688063 558 62826 Y433 G Y R G T C T Y E K I Q T Y R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.8 98.5 N.A. 97.1 31.1 N.A. 84.9 75.2 27.6 60.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 100 99.8 N.A. 99.2 48.8 N.A. 92.6 89 45.6 78.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 46.6 N.A. 93.3 80 0 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 100 93.3 26.6 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 80 10 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 10 10 0 0 0 0 80 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 90 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 90 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 0 0 0 0 0 0 10 0 60 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 90 0 0 0 % Q
% Arg: 0 0 80 0 0 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 0 0 0 0 70 0 0 10 0 0 0 0 60 0 0 % S
% Thr: 0 0 0 0 10 10 80 10 0 0 0 0 20 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 80 0 10 0 0 0 80 0 0 0 10 0 90 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _