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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL23
All Species:
19.39
Human Site:
Y11
Identified Species:
47.41
UniProt:
Q8NBE8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NBE8
NP_653312.2
558
63923
Y11
K
G
Q
E
D
Y
I
Y
L
F
K
D
S
T
H
Chimpanzee
Pan troglodytes
XP_515889
558
63891
Y11
K
G
Q
E
D
Y
I
Y
L
F
N
D
S
T
H
Rhesus Macaque
Macaca mulatta
XP_001104950
558
63891
Y11
K
G
Q
D
D
Y
I
Y
L
F
K
D
S
T
H
Dog
Lupus familis
XP_545514
558
63871
Y11
K
G
Q
E
D
Y
I
Y
L
F
K
D
T
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQU2
558
63821
F11
K
G
Q
E
D
Y
I
F
H
F
K
D
S
S
H
Rat
Rattus norvegicus
Q56A24
600
68346
F40
S
L
T
G
H
E
Y
F
D
F
S
S
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514763
558
63599
Y11
K
G
Q
E
D
Y
T
Y
V
F
K
D
P
S
H
Chicken
Gallus gallus
XP_426582
558
63291
F11
P
G
Q
E
D
Y
V
F
A
Y
R
D
S
S
H
Frog
Xenopus laevis
Q6INL2
589
66424
H15
L
E
F
C
L
P
S
H
S
D
A
I
L
S
G
Zebra Danio
Brachydanio rerio
XP_688063
558
62826
Y11
N
A
Q
S
G
Y
S
Y
D
F
Y
D
A
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
98.5
N.A.
97.1
31.1
N.A.
84.9
75.2
27.6
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
100
99.8
N.A.
99.2
48.8
N.A.
92.6
89
45.6
78.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
80
6.6
N.A.
73.3
53.3
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
20
N.A.
86.6
86.6
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
10
0
10
0
10
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
70
0
0
0
20
10
0
80
0
0
0
% D
% Glu:
0
10
0
60
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
30
0
80
0
0
0
0
0
% F
% Gly:
0
70
0
10
10
0
0
0
0
0
0
0
10
0
10
% G
% His:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
80
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
10
0
0
0
% I
% Lys:
60
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% K
% Leu:
10
10
0
0
10
0
0
0
40
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
0
10
0
0
20
0
10
0
10
10
50
60
10
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
0
0
10
30
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
80
10
60
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _