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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM1B All Species: 20.91
Human Site: S776 Identified Species: 51.11
UniProt: Q8NB78 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NB78 NP_694587.3 823 92226 S776 S F V K T G G S G E A Y D I I
Chimpanzee Pan troglodytes XP_518258 923 103081 S876 S F V K T G G S G E A Y D I I
Rhesus Macaque Macaca mulatta XP_001097626 619 68608 G573 F V K T G G S G E A Y D I I A
Dog Lupus familis XP_535900 558 62499 G512 F V K T G G S G E A Y D I I A
Cat Felis silvestris
Mouse Mus musculus Q8CIG3 826 92614 S779 S F V K T F G S G E A Y D I I
Rat Rattus norvegicus NP_001100813 824 92537 S777 S F V K T F G S G E A Y D I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418920 896 99632 S849 S F V K T G G S G E A Y D I I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW97 890 98370 S770 S Y V S V G S S G S D Y D L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21988 824 93415 G768 F V P F G S D G D A T Y N Q L
Sea Urchin Strong. purpuratus XP_782860 837 93222 S788 K Q T V P N P S K Y F V T Q W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 74.4 65.3 N.A. 89.7 89.8 N.A. N.A. 78.4 N.A. N.A. N.A. 20.7 N.A. 35.1 50
Protein Similarity: 100 89 74.8 66.7 N.A. 94.3 94.9 N.A. N.A. 84.2 N.A. N.A. N.A. 39.7 N.A. 53.8 69.4
P-Site Identity: 100 100 13.3 13.3 N.A. 93.3 93.3 N.A. N.A. 100 N.A. N.A. N.A. 46.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 13.3 13.3 N.A. 93.3 93.3 N.A. N.A. 100 N.A. N.A. N.A. 66.6 N.A. 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 30 50 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 10 0 10 20 60 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 20 50 0 0 0 0 0 % E
% Phe: 30 50 0 10 0 20 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 30 60 50 30 60 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 20 70 50 % I
% Lys: 10 0 20 50 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 20 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 0 0 10 0 10 30 70 0 10 0 0 0 0 0 % S
% Thr: 0 0 10 20 50 0 0 0 0 0 10 0 10 0 0 % T
% Val: 0 30 60 10 10 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 10 0 0 0 0 0 0 0 10 20 70 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _