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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KDM1B
All Species:
17.58
Human Site:
S384
Identified Species:
42.96
UniProt:
Q8NB78
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB78
NP_694587.3
823
92226
S384
P
K
D
Y
H
N
K
S
V
I
I
I
G
A
G
Chimpanzee
Pan troglodytes
XP_518258
923
103081
S484
P
K
D
Y
H
N
K
S
V
I
I
I
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001097626
619
68608
R213
T
V
L
E
A
K
D
R
I
G
G
R
V
W
D
Dog
Lupus familis
XP_535900
558
62499
R152
T
V
L
E
A
K
D
R
I
G
G
R
V
W
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIG3
826
92614
S390
P
K
H
Y
H
N
K
S
V
L
V
V
G
A
G
Rat
Rattus norvegicus
NP_001100813
824
92537
S388
P
K
H
Y
H
N
K
S
V
L
V
V
G
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418920
896
99632
S458
P
K
E
Y
H
N
K
S
V
I
I
V
G
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW97
890
98370
C390
D
F
N
Y
A
G
D
C
P
V
S
L
G
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21988
824
93415
A382
I
D
A
V
L
F
E
A
K
D
R
F
G
G
R
Sea Urchin
Strong. purpuratus
XP_782860
837
93222
K423
C
R
D
V
G
M
G
K
I
I
V
I
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
74.4
65.3
N.A.
89.7
89.8
N.A.
N.A.
78.4
N.A.
N.A.
N.A.
20.7
N.A.
35.1
50
Protein Similarity:
100
89
74.8
66.7
N.A.
94.3
94.9
N.A.
N.A.
84.2
N.A.
N.A.
N.A.
39.7
N.A.
53.8
69.4
P-Site Identity:
100
100
0
0
N.A.
73.3
73.3
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
13.3
N.A.
6.6
40
P-Site Similarity:
100
100
6.6
6.6
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
N.A.
N.A.
33.3
N.A.
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
30
0
0
10
0
0
0
0
0
60
10
% A
% Cys:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
10
30
0
0
0
30
0
0
10
0
0
0
10
20
% D
% Glu:
0
0
10
20
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
10
10
0
0
20
20
0
80
10
60
% G
% His:
0
0
20
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
30
40
30
30
0
0
0
% I
% Lys:
0
50
0
0
0
20
50
10
10
0
0
0
0
0
0
% K
% Leu:
0
0
20
0
10
0
0
0
0
20
0
10
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
50
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
20
0
0
10
20
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
10
0
0
0
0
% S
% Thr:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
20
0
20
0
0
0
0
50
10
30
30
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% W
% Tyr:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _