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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM184A
All Species:
9.09
Human Site:
S593
Identified Species:
16.67
UniProt:
Q8NB25
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB25
NP_001093881.1
1140
132965
S593
E
L
D
L
T
K
D
S
L
K
E
T
K
D
A
Chimpanzee
Pan troglodytes
XP_001163920
1138
132636
S591
E
L
D
L
T
K
D
S
L
K
E
T
K
D
A
Rhesus Macaque
Macaca mulatta
XP_001110223
1143
133027
S596
E
L
D
L
T
K
D
S
L
K
E
T
K
D
A
Dog
Lupus familis
XP_533480
1140
132525
R593
E
L
D
L
T
K
G
R
L
K
D
T
K
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q0KK56
942
107582
E451
K
S
V
C
S
T
V
E
V
E
R
K
K
L
K
Rat
Rattus norvegicus
Q9JLT0
1976
228947
A1056
T
R
Q
E
L
E
K
A
K
R
K
L
D
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521819
525
61386
A34
E
E
I
Q
Q
I
L
A
E
T
R
E
K
I
L
Chicken
Gallus gallus
P10587
1979
228777
I1062
S
R
Q
E
L
E
K
I
K
R
K
L
E
G
E
Frog
Xenopus laevis
NP_001087755
1113
130052
R567
E
L
D
V
T
S
E
R
L
R
E
T
N
N
S
Zebra Danio
Brachydanio rerio
XP_683302
1145
133823
R596
E
L
D
A
T
R
A
R
L
R
E
T
S
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
N1298
S
I
N
D
Q
L
E
N
L
R
K
A
K
T
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
L597
K
D
A
E
I
L
N
L
R
K
Q
L
E
K
E
Sea Urchin
Strong. purpuratus
XP_795044
1073
122967
E527
N
L
E
K
A
Q
K
E
G
R
E
T
G
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
94.2
N.A.
26.3
20.8
N.A.
38.1
20.9
66
58.4
N.A.
20.4
N.A.
21.9
32.8
Protein Similarity:
100
99.3
99.1
97.1
N.A.
46.1
36.8
N.A.
42.2
36.9
83.3
78.4
N.A.
34.6
N.A.
44.8
54.5
P-Site Identity:
100
100
100
80
N.A.
6.6
0
N.A.
13.3
0
46.6
46.6
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
26.6
N.A.
20
26.6
80
66.6
N.A.
53.3
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
0
8
16
0
0
0
8
0
0
31
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
47
8
0
0
24
0
0
0
8
0
8
31
0
% D
% Glu:
54
8
8
24
0
16
16
16
8
8
47
8
16
0
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
0
0
8
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
8
0
8
0
0
0
0
0
8
0
% I
% Lys:
16
0
0
8
0
31
24
0
16
39
24
8
54
8
8
% K
% Leu:
0
54
0
31
16
16
8
8
54
0
0
24
0
8
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
0
8
8
0
0
0
0
8
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
8
16
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
0
16
0
0
0
8
0
24
8
47
16
0
0
0
0
% R
% Ser:
16
8
0
0
8
8
0
24
0
0
0
0
8
8
8
% S
% Thr:
8
0
0
0
47
8
0
0
0
8
0
54
0
8
0
% T
% Val:
0
0
8
8
0
0
8
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _