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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM184A
All Species:
22.42
Human Site:
S579
Identified Species:
41.11
UniProt:
Q8NB25
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB25
NP_001093881.1
1140
132965
S579
L
I
A
S
L
Q
D
S
Q
E
R
L
Q
N
E
Chimpanzee
Pan troglodytes
XP_001163920
1138
132636
S577
L
I
A
S
L
Q
D
S
Q
E
R
L
Q
N
E
Rhesus Macaque
Macaca mulatta
XP_001110223
1143
133027
S582
L
I
A
S
L
Q
D
S
Q
E
R
L
Q
T
E
Dog
Lupus familis
XP_533480
1140
132525
S579
L
I
A
S
L
Q
D
S
Q
E
R
L
Q
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q0KK56
942
107582
K437
K
R
L
E
D
L
V
K
K
H
T
M
E
M
K
Rat
Rattus norvegicus
Q9JLT0
1976
228947
R1042
M
I
S
D
L
E
E
R
L
K
K
E
E
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521819
525
61386
A20
E
H
E
S
A
I
Q
A
L
K
E
A
H
E
E
Chicken
Gallus gallus
P10587
1979
228777
R1048
M
I
S
E
L
E
V
R
L
K
K
E
E
K
S
Frog
Xenopus laevis
NP_001087755
1113
130052
T553
H
I
T
S
L
K
D
T
Q
D
R
L
Q
K
E
Zebra Danio
Brachydanio rerio
XP_683302
1145
133823
A582
H
I
S
N
L
K
D
A
Q
K
K
L
L
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
K1284
V
L
A
D
M
R
H
K
H
S
Q
E
L
N
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
Y583
L
T
R
T
L
E
E
Y
R
E
R
I
T
G
K
Sea Urchin
Strong. purpuratus
XP_795044
1073
122967
T513
R
I
S
S
L
Q
Q
T
N
A
Q
L
L
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.9
94.2
N.A.
26.3
20.8
N.A.
38.1
20.9
66
58.4
N.A.
20.4
N.A.
21.9
32.8
Protein Similarity:
100
99.3
99.1
97.1
N.A.
46.1
36.8
N.A.
42.2
36.9
83.3
78.4
N.A.
34.6
N.A.
44.8
54.5
P-Site Identity:
100
100
93.3
100
N.A.
0
13.3
N.A.
13.3
13.3
60
40
N.A.
13.3
N.A.
26.6
33.3
P-Site Similarity:
100
100
93.3
100
N.A.
26.6
60
N.A.
26.6
53.3
80
80
N.A.
46.6
N.A.
66.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
39
0
8
0
0
16
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
8
0
47
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
8
16
0
24
16
0
0
39
8
24
24
24
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
16
8
0
0
0
0
8
0
8
8
0
0
8
0
0
% H
% Ile:
0
70
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
0
0
16
0
16
8
31
24
0
0
24
16
% K
% Leu:
39
8
8
0
77
8
0
0
24
0
0
54
24
0
0
% L
% Met:
16
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
31
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
39
16
0
47
0
16
0
39
0
0
% Q
% Arg:
8
8
8
0
0
8
0
16
8
0
47
0
0
0
0
% R
% Ser:
0
0
31
54
0
0
0
31
0
8
0
0
0
0
16
% S
% Thr:
0
8
8
8
0
0
0
16
0
0
8
0
8
8
8
% T
% Val:
8
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _