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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD1
All Species:
19.7
Human Site:
Y325
Identified Species:
48.15
UniProt:
Q8NB12
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB12
NP_938015.1
490
56617
Y325
K
A
R
S
E
G
L
Y
H
E
V
V
K
L
C
Chimpanzee
Pan troglodytes
XP_514316
454
52196
E286
L
R
D
Q
Y
C
F
E
C
D
C
F
R
C
Q
Rhesus Macaque
Macaca mulatta
XP_001093225
479
54825
A317
K
E
A
L
Q
N
G
A
N
Q
R
S
E
V
L
Dog
Lupus familis
XP_852104
490
56440
Y325
K
A
R
S
E
G
L
Y
H
E
V
V
K
L
C
Cat
Felis silvestris
Mouse
Mus musculus
P97443
485
55988
Y320
K
A
R
S
E
G
L
Y
H
E
V
V
K
L
C
Rat
Rattus norvegicus
Q7M6Z3
433
49630
N284
V
E
I
R
K
L
S
N
P
P
Q
A
E
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510487
490
56179
Y325
K
A
R
S
E
G
V
Y
H
E
V
V
K
L
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085463
478
54748
Y308
K
A
R
S
E
G
S
Y
H
Q
V
V
K
L
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
S278
E
L
C
G
W
T
M
S
K
D
H
F
E
L
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
F312
R
D
P
E
E
K
G
F
V
C
Q
K
C
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
85.5
96.1
N.A.
93.6
28.5
N.A.
87.5
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
46.1
90.1
99.1
N.A.
97.7
49.5
N.A.
95.5
N.A.
84.9
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
100
0
N.A.
93.3
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
40
100
N.A.
100
13.3
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
10
0
0
0
0
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
10
0
0
10
0
0
10
10
10
0
10
10
60
% C
% Asp:
0
10
10
0
0
0
0
0
0
20
0
0
0
0
0
% D
% Glu:
10
20
0
10
60
0
0
10
0
40
0
0
30
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
20
0
0
0
% F
% Gly:
0
0
0
10
0
50
20
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
50
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
60
0
0
0
10
10
0
0
10
0
0
10
50
0
0
% K
% Leu:
10
10
0
10
0
10
30
0
0
0
0
0
0
70
20
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
0
0
0
20
20
0
0
0
10
% Q
% Arg:
10
10
50
10
0
0
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
0
50
0
0
20
10
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
10
0
50
50
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _