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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMYD1
All Species:
22.73
Human Site:
S185
Identified Species:
55.56
UniProt:
Q8NB12
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NB12
NP_938015.1
490
56617
S185
N
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Chimpanzee
Pan troglodytes
XP_514316
454
52196
P167
Q
D
A
S
Q
L
P
P
A
F
D
L
F
E
A
Rhesus Macaque
Macaca mulatta
XP_001093225
479
54825
S185
N
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Dog
Lupus familis
XP_852104
490
56440
S185
S
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
P97443
485
55988
S180
N
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Rat
Rattus norvegicus
Q7M6Z3
433
49630
L164
H
Q
F
Y
S
K
H
L
E
F
P
D
H
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510487
490
56179
S185
N
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085463
478
54748
S180
S
C
N
G
F
T
L
S
D
Q
R
G
L
Q
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09415
429
48527
N159
I
N
S
F
V
V
G
N
S
T
G
N
P
I
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7XJS0
480
54809
N182
D
L
R
E
I
A
E
N
F
S
K
F
S
C
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.7
85.5
96.1
N.A.
93.6
28.5
N.A.
87.5
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
46.1
90.1
99.1
N.A.
97.7
49.5
N.A.
95.5
N.A.
84.9
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
0
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
20
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
10
0
0
0
0
0
70
% A
% Cys:
0
60
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
10
0
0
0
0
0
0
60
0
10
10
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
10
10
60
0
0
0
10
20
0
10
10
0
0
% F
% Gly:
0
0
0
60
0
0
10
0
0
0
10
60
0
0
10
% G
% His:
10
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
0
0
0
10
60
10
0
0
0
10
60
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
10
60
0
0
0
0
20
0
0
0
10
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
10
0
10
0
0
% P
% Gln:
10
10
0
0
10
0
0
0
0
60
0
0
0
60
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
60
0
0
0
0
% R
% Ser:
20
0
10
10
10
0
0
60
10
10
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
60
0
0
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _